Zobrazeno 1 - 10
of 34
pro vyhledávání: '"M W, Jann"'
Lack of CYP3A4 inhibition by grapefruit juice and ketoconazole upon clozapine administration in vivo
Publikováno v:
Drug metabolism and drug interactions. 18(3-4)
The drug-food and drug-drug interaction between grapefruit juice (GFJ) and ketoconazole (KETO) was evaluated in schizophrenic patients given a single dose of clozapine (CLZ). CLZ is metabolized primarily by CYP isozymes 3A4 and 1A2 to two principal m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a4fac0278b3709df235126ac8cb7dab
https://pubmed.ncbi.nlm.nih.gov/11791889
https://pubmed.ncbi.nlm.nih.gov/11791889
Autor:
Y. W. Francis Lam, M. W. Jann
Publikováno v:
Journal of Pharmacy Practice. 6:44-46
The discipline of pharmacogenetics will continue to expand as scientific and clinical investigations increase our understanding of genetic variabilities in drug metabolism and response. These research efforts will include determination of molecular m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ff98bd4a752485115f40fdae5c22bd0
https://doi.org/10.1177/089719009300600105
https://doi.org/10.1177/089719009300600105
Publikováno v:
Journal of the American Pharmaceutical Association (Washington, D.C. : 1996). 40(5 Suppl 1)
The prevalence of AD, the most common form of dementia, is likely to double in the next 20 years. Although the cause of AD is unknown, risk factors include aging, genetic predisposition, and head trauma. The cholinesterase inhibitors (tacrine, donepe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::af16f8f9eeca84e8bfbdb0c9fc21466e
https://pubmed.ncbi.nlm.nih.gov/11029868
https://pubmed.ncbi.nlm.nih.gov/11029868
Autor:
H D, Desai, M W, Jann
Publikováno v:
Journal of the American Pharmaceutical Association (Washington, D.C. : 1996). 40(4)
To promote pharmacists' understanding and recognition of major depression in women and to review gender/sex-specific differences in its prevalence, etiology, risk factors, clinical features, course, and management.Clinical literature on this topic in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::00b443d03c7182664c4d9b8e97980871
https://pubmed.ncbi.nlm.nih.gov/10932463
https://pubmed.ncbi.nlm.nih.gov/10932463
Publikováno v:
Clinical therapeutics. 21(1)
This prospective, randomized, double-masked, placebo-controlled, parallel-group study assessed the safety and efficacy of 2 dosage regimens of once-daily metrifonate in patients with probable Alzheimer's disease (AD) of mild-to-moderate severity. A t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0fe5825648dd11177b13299a17e58e77
https://pubmed.ncbi.nlm.nih.gov/10090427
https://pubmed.ncbi.nlm.nih.gov/10090427
Publikováno v:
Pharmacotherapy. 18(2)
To compare the relative bioavailability of two 16-mg extemporaneously prepared suppository formulations with that of an 8-mg commercially available oral tablet.Prospective, crossover bioavailability study.Inpatient clinical research center.Sixteen yo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::07eb2f2ea56cab3452ffcbda0995b093
https://pubmed.ncbi.nlm.nih.gov/9545148
https://pubmed.ncbi.nlm.nih.gov/9545148
Publikováno v:
Pharmacotherapy. 17(3)
Venlafaxine, a phenylethylamine, and nefazodone, a phenylpiperazine compound, are the newest antidepressants to receive approval of the Food and Drug Administration and to be marketed in the United States. Both strongly inhibit serotonin (5-HT) reupt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c59d94ef7c39c1978053b3cf7c418956
https://pubmed.ncbi.nlm.nih.gov/9165554
https://pubmed.ncbi.nlm.nih.gov/9165554
Publikováno v:
The Journal of clinical psychiatry. 57(7)
Haloperidol decanoate is a long-acting depot antipsychotic agent used for the treatment of schizophrenic patients. The decanoate formulation was developed to treat schizophrenics who have a history of noncompliance with oral medication. Studies of te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4eee96d0f7941b58e61b160e24a59197
https://pubmed.ncbi.nlm.nih.gov/8666571
https://pubmed.ncbi.nlm.nih.gov/8666571
Publikováno v:
International journal of clinical pharmacology and therapeutics. 34(1)
The disposition of remoxipride was evaluated in 13 male chronic schizophrenic patients. A single 150 mg dose of remoxipride was administered and blood sampling performed over the following 48 hours. The mean (SD) oral clearance and half-life of remox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ff1554a6d1b1565ddddb890ad81bbbdc
https://pubmed.ncbi.nlm.nih.gov/8688992
https://pubmed.ncbi.nlm.nih.gov/8688992
Publikováno v:
Archives internationales de pharmacodynamie et de therapie. 328(2)
Clozapine and its metabolite clozapine-N-oxide (0.5 mg/kg) were administered intraperitoneally to guinea-pigs. Significant amounts of clozapine were detected in plasma, liver, frontal cortex and caudate after clozapine-N-oxide administration. The amo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::117ed3d2a0e27ad9bc4cc347202a4285
https://pubmed.ncbi.nlm.nih.gov/7710309
https://pubmed.ncbi.nlm.nih.gov/7710309