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pro vyhledávání: '"M W, Germann"'
Publikováno v:
Journal of biomolecular NMR. 18(4)
Nucleic acid duplexes featuring a single alpha-anomeric thymidine inserted into each DNA strand via 3'-3' and 5'-5' phosphodiester linkages exhibit local conformational dynamics that are not adequately depicted by conventional restrained molecular dy
Autor:
J M, Aramini, M W, Germann
Publikováno v:
Biochemistry and cell biology = Biochimie et biologie cellulaire. 76(2-3)
We present a summary of our research to date on a family of self-complementary DNA decamers containing single alpha-anomeric nucleotides flanked by 3'-3' and 5'-5' phosphodiester linkages from the perspective of the salient NMR techniques employed to
Publikováno v:
Biochemistry and cell biology = Biochimie et biologie cellulaire. 76(2-3)
We have correlated the structural perturbations caused by DNA mismatches with the enzymatic data of the interaction of the restriction endonuclease EcoRI with DNA. Oligonucleotides d(CGAGAATTCTCA5GAXAATTCT) (X = G, A, T) and d(CGCGAATTYGCGT4CGCXAATTC
Publikováno v:
Methods in enzymology. 261
Publikováno v:
Biochemistry. 32(2)
The structure of the oligodeoxynucleotide (3')T8(5')-(5')C4A8(3') hairpin in aqueous solution was studied by two-dimensional (2D) proton and phosphorus nuclear magnetic resonance (NMR) spectroscopy. At 2.5 mM and 10 degrees C, the molecule exists pre