Zobrazeno 1 - 10
of 39
pro vyhledávání: '"M W, Brechbiel"'
Autor:
Haini Yu, M W Brechbiel, J B Delehanty, Mehraban Khosraviani, R C Blake nd, S C Lorbach, Andrey R. Pavlov, Diane A. Blake
Publikováno v:
Bioconjugate Chemistry. 11:267-277
A monoclonal antibody (2C12) that recognizes a Pb(II)-cyclohexyldiethylenetriamine pentaacetic acid complex was produced by the injection of BALB/c mice with a Pb(II)-chelate complex covalently coupled to a carrier protein. The ability of purified an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b34bcb580022ed244f9cacd231fcda7b
https://doi.org/10.1021/bc9901548
https://doi.org/10.1021/bc9901548
Autor:
F. P. Auteri, Paul C. Lauterbur, D. S. Schneider, M. W. Brechbiel, O. A. Gansow, R. L. Belford, Robert B. Clarkson, J. W. Chen, Erik C. Wiener
Publikováno v:
Journal of the American Chemical Society. 118:7774-7782
We studied the molecular dynamics of vanadyl−chelate complexes covalently attached to the surface of cascade polymers, dendrimers. The rotational correlation times of the ion−chelate complex were determined from computer simulations of their EPR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe59805a8527dfcc7fc7b76e0c5048cc
https://doi.org/10.1021/ja9536126
https://doi.org/10.1021/ja9536126
Autor:
K. Garmestani, D. E. Milenic, M. W. Brechbiel, Celeste A. S. Regino, P. L. Choyke, Karen J. Wong, E. H. Holmes
Better tumor markers are needed for early diagnosis and staging of prostate cancer, and for monitoring therapeutic response than the currently used prostate specific antigen (PSA). Prostate specific membrane antigen (PSMA) is highly expressed on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33cacbab70aa3bc35dfcbb35a91805e9
https://europepmc.org/articles/PMC2678849/
https://europepmc.org/articles/PMC2678849/
Autor:
K. Garmestani, W. C. Eckelman, A. T. Yordanov, Michael G. Stabin, Saed Mirzadeh, M. W. Brechbiel, T. A. Waldmann, Stephen J. Kennel
Publikováno v:
Radiation research. 157(6)
Astatine-211, an alpha-particle emitter, was employed in a model system for vascular-targeted radioimmunotherapy of small tumors in mouse lung to compare its performance relative to other radioisotopes in the same system. Astatine-211 was coupled to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d22f2afb37459845746ec40d764c06
https://pubmed.ncbi.nlm.nih.gov/12005541
https://pubmed.ncbi.nlm.nih.gov/12005541
Autor:
A, Lövqvist, J L, Humm, A, Sheikh, R D, Finn, J, Koziorowski, S, Ruan, K S, Pentlow, A, Jungbluth, S, Welt, F T, Lee, M W, Brechbiel, S M, Larson
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 42(8)
Absorbed doses in (90)Y radioimmunotherapy are usually estimated by extrapolating from (111)In imaging data. PET using (86)Y (beta(+) 33%; half-life, 14.7 h) as a surrogate radiolabel could be a more accurate alternative. The aim of this study was to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4a80caf5b1e055d5edff56653de71b1f
https://pubmed.ncbi.nlm.nih.gov/11483692
https://pubmed.ncbi.nlm.nih.gov/11483692
Autor:
S V, Govindan, D M, Goldenberg, S E, Elsamra, G L, Griffiths, G L, Ong, M W, Brechbiel, J, Burton, G, Sgouros, M J, Mattes
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 41(12)
We demonstrated previously that human B-cell lymphomas were effectively and specifically killed in vitro by an antibody to CD74 (LL1) linked to (111)In or other Auger electron emitters. This study was intended to more accurately compare the potency a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1a09303a7790b059297a0a9b4ce8f42e
https://pubmed.ncbi.nlm.nih.gov/11138697
https://pubmed.ncbi.nlm.nih.gov/11138697
Publikováno v:
Angewandte Chemie (International ed. in English). 39(9)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2b1a3eedb9b02d35adf0e42b3b2615bf
https://pubmed.ncbi.nlm.nih.gov/10820462
https://pubmed.ncbi.nlm.nih.gov/10820462
Autor:
H, Kobayashi, C H, Kao, R J, Kreitman, N, Le, M K, Kim, M W, Brechbiel, C H, Paik, I, Pastan, J A, Carrasquillo
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 41(4)
The use of immunotoxins for cancer therapy is an attractive strategy that exploits the targeting specificity of monoclonal antibodies and their fragments as well as the exquisite toxicity of the toxins. However, few studies of immunotoxins have evalu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f33a3bda4ebf9d9450e277728dfd4421
https://pubmed.ncbi.nlm.nih.gov/10768579
https://pubmed.ncbi.nlm.nih.gov/10768579
Autor:
D J, Buchsbaum, B E, Rogers, M B, Khazaeli, M S, Mayo, D E, Milenic, S V, Kashmiri, C J, Anderson, L L, Chappell, M W, Brechbiel, D T, Curiel
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5
Novel strategies to increase the therapeutic ratio in clinical radioimmunotherapy studies are needed. Limitations to radioimmunotherapy include bone marrow suppression due to the long circulating half-life of radiolabeled monoclonal antibodies (mAbs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::27b351f7f8f74f5bed773a6b8347fe8e
https://pubmed.ncbi.nlm.nih.gov/10541342
https://pubmed.ncbi.nlm.nih.gov/10541342
Publikováno v:
Journal of magnetic resonance imaging : JMRI. 9(2)
A series of high-generation (G) ethylenediamine-core polyamidoamine (PAMAM) dendrimers corresponding to G = 5, 7, 9, and 10 were conjugated with the bifunctional chelate 2-(4-isothiocyanatobenzyl)- 1,4,7,10-tetraazacyclododecane-N,N',N",N"'-tetraacet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b490a3617bb9a1d266b6aa71e5814063
https://pubmed.ncbi.nlm.nih.gov/10077036
https://pubmed.ncbi.nlm.nih.gov/10077036