Neural substrates of cognitive impairment in a NMDAR hypofunction mouse model of schizophrenia and partial rescue by risperidone

Autor: Cristina Delgado-Sallent, Thomas Gener, Pau Nebot, Cristina López-Cabezón, M. Victoria Puig

Publikováno v: Frontiers in Cellular Neuroscience, Vol 17 (2023)

N-methyl D-aspartate receptor (NMDAR) hypofunction is a pathophysiological mechanism relevant for schizophrenia. Acute administration of the NMDAR antagonist phencyclidine (PCP) induces psychosis in patients and animals while subchronic PCP (sPCP) pr

Externí odkaz: https://doaj.org/article/9c9e714f752d459d86afef747b55b3b6

Postnatal environmental enrichment enhances memory through distinct neural mechanisms in healthy and trisomic female mice

Autor: Maria Alemany-González, Marta Vilademunt, Thomas Gener, M. Victoria Puig

Publikováno v: Neurobiology of Disease, Vol 173, Iss , Pp 105841- (2022)

Stimulating lifestyles have powerful effects on cognitive abilities, especially when they are experienced early in life. Cognitive therapies are widely used to improve cognitive impairment due to intellectual disability, aging, and neurodegeneration,

Externí odkaz: https://doaj.org/article/6e2802efb3bf4f35aa659ec44ee01d70

Prefrontal–accumbens neural dynamics abnormalities in mice vulnerable to develop food addiction

Autor: Pablo Calvé, Thomas Gener, Laura Ribalta-Vilella, Sami Kummer, Pau Nebot, Elena Martín-García, M. Victoria Puig, Rafael Maldonado

Food addiction is characterized by a loss of behavioral control over food intake and is closely associated with several eating disorders, including obesity and binge eating. Despite its high prevalence, the underlying neural mechanisms of food addict

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::43bbddb38c12aaa4934191bc8cb8751c
https://doi.org/10.1101/2022.11.22.517466

Reversible photocontrol of dopaminergic transmission in wild-type animals

Autor: Carlo Matera, Pablo Calvé, Verònica Casadó-Anguera, Rosalba Sortino, Alexandre M. J. Gomila, Estefanía Moreno, Thomas Gener, Cristina Delgado-Sallent, Pau Nebot, Davide Costazza, Sara Conde-Berriozabal, Mercè Masana, Jordi Hernando, Vicent Casadó, M. Victoria Puig, Pau Gorostiza

Publikováno v: ORCID
International Journal of Molecular Sciences; Volume 23; Issue 17; Pages: 10114
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Dipòsit Digital de la UB
Universidad de Barcelona

Understanding the dopaminergic system is a priority in neurobiology and neuropharmacology. Dopamine receptors are involved in the modulation of fundamental physiological functions, and dysregulation of dopaminergic transmission is associated with maj

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::921d906e8fe6bf668fc1abf5545eb3ce
https://doi.org/10.26434/chemrxiv-2022-8jlxp

Postnatal environmental enrichment enhances memory by shaping hippocampal-prefrontal theta and gamma rhythms in diploid and trisomic female mice

Autor: Maria Alemany-González, Marta Vilademunt, Thomas Gener, Pau Nebot, M. Victoria Puig

Rich social, physical, and cognitively stimulating lifestyles have powerful effects on cognitive abilities, especially when they are experienced early in life. Cognitive therapies are widely used to attenuate cognitive impairment due to intellectual

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0b353cc962d93c8e350aabfb276cf63d
https://doi.org/10.1101/2022.02.16.480741