Zobrazeno 1 - 4
of 4
pro vyhledávání: '"M V Toth"'
Autor:
Suzanne Metz, Mahima Trivedi, William M. Moore, Timothy J. Hagen, Mark E. Zupec, Jane R. Connor, Mark G. Currie, B. S. Pitzele, Kam F. Fok, M. V. Toth, Pamela T. Manning, Ronald Keith Webber, D. W. Hansen, Gina M. Jerome, F. S. Tjoeng
Publikováno v:
Journal of Medicinal Chemistry. 41:96-101
A series of analogues of 2-iminopiperidine have been prepared and shown to be potent inhibitors of the human nitric oxide synthase (NOS) isoforms. Methyl substitutions on the 4-position (3) or 4- and 6-positions (8) afforded the most potent analogues
Autor:
M V Toth, Arthur J. Wittwer, R.C. Wiegand, Christine E. Smith, L S Carr, K L Duffin, M L Bryant, Barry C. Holwerda
Publikováno v:
Journal of Biological Chemistry. 269:25911-25915
The human cytomegalovirus UL80 protease was expressed in Escherichia coli and purified by metal-chelate chromatography using a histidine tag engineered at the amino terminus. Cleavage of the 30-kDa protease at an internal site, VEA/A144, resulted in
Autor:
D L, Flynn, D P, Becker, V M, Dilworth, M K, Highkin, P J, Hippenmeyer, K A, Houseman, L M, Levine, M, Li, A E, Moormann, A, Rankin, M V, Toth, C I, Villamil, A J, Wittwer, B C, Holwerda
Publikováno v:
Drug design and discovery. 15(1)
The herpesvirus protease is a recently identified enzyme which is essential for viral replication. It is found in all herpesviruses and offers a new molecular target for therapeutic intervention. Its genomic structure has recently been described and
Autor:
Kálmán Kovács, G. Jahreis, Siegfried Fittkau, Lajos Baláspiri, M. V. Toth, B. Hartrodt, T. Takacs, E. Berger, Klaus Neubert
Publikováno v:
Chemischer Informationsdienst. 16