Výsledky vyhledávání - "M V Alfimova"

[Epigenetic research of cognitive deficit in schizophrenia: some methodological considerations]

Autor: T V Lezheiko, M V Alfimova

Publikováno v: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 117(10)

To highlights the problems of assessing cognitive deficits in schizophrenia, relevant to the epigenetic, as well as a wide range of other approaches to the search for biological bases of cognition.The literature on the weaknesses in the evaluation of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87dc76cd67d945f58042d89c0103c656
https://pubmed.ncbi.nlm.nih.gov/29171493

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[Methylation of the Reelin Gene Promoter in Peripheral Blood and Its Relationship with the Cognitive Function of Schizophrenia Patients]

Autor: M V, Alfimova, N V, Kondratiev, A K, Golov, V E, Golimbet

Publikováno v: Molekuliarnaia biologiia. 52(5)

There is a decrease in the expression of the reelin gene (RELN) in the brain of schizophrenia patients, which can underlie observed cognitive abnormalities. It is suggested that this decrease is caused by the hypermethylation of the RELN promoter. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d2264f659b01388500fe04ad5678b930
https://pubmed.ncbi.nlm.nih.gov/30363053

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[Polymorphism C366G of gene GRIN2B and verbal episodic memory: No association with schizophrenia]

Autor: M V, Alfimova, V E, Golimbet, G I, Korovaitseva, T V, Lezheiko, L I, Abramova, V G, Kaleda

Publikováno v: Genetika. 52(6)

The present study searched for associations between gene GRIN2B (glutamate receptor, ionotropic, N-methyl-D-aspartate, subunit 2B) and component processes of verbal episodic memory in schizophrenic patients. The Rey Auditory Verbal Learning Test (RAV

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::eff7d30357462418196cdd48749ecd75
https://pubmed.ncbi.nlm.nih.gov/29368832

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[Analysis of the association of interleukin 4 and interleukin 10 gene variants with basic personality traits]

Autor: V E, Golimbet, M V, Alfimova, G I, Korovaitseva, T V, Lezheiko

Publikováno v: Molekuliarnaia biologiia. 50(6)

There is growing evidence that serum levels of various inflammation markers are associated with personality traits. However, only few studies investigated the link between genetic variants of cytokine encoding genes and psychological characteristics.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::20d812ccff48c230fde9bc05d5a9c7fb
https://pubmed.ncbi.nlm.nih.gov/28064311

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Results and promises of genetics of cognitive impairment in schizophrenia: epigenetic approaches

Autor: M. V. Alfimova, N. V. Kondratiev, V. E. Golimbet

Publikováno v: Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 117:130

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::08ece3b9936a4e5acc9a5f77ca5be2e3
https://doi.org/10.17116/jnevro201711721130-135

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[The association of COMT and DRD2 gene polymorphisms with a cognitive ability to understand others in schizophrenic patients]

Autor: M V, Alfimova, V E, Golimbet, G I, Korovaĭtseva, E V, Aksenova, T V, Lezheĭko, L I, Abramova, N Iu, Kolesina, I M, Anua, T M, Savel'eva

Publikováno v: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 113(8)

To evaluate a role of dopamine transmission in the theory of mind (ToM) dysfunction in schizophrenia, authors studied the association of ToM with COMT and DRD2 gene polymorphisms in 209 patients with schizophrenia and 172 healthy people. All subjects

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3f744e12b1c5a71d8d1dde5e1a73c2d5
https://pubmed.ncbi.nlm.nih.gov/24077552

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[Application of EEG coherence analysis for evaluation of the brain integrative activity in schizophrenia]

Autor: T S, Mel'nikova, M V, Alfimova

Publikováno v: Uspekhi fiziologicheskikh nauk. 44(2)

In this review we aim to systematize the evidence on changes in schizophrenic brain functional connectivity assessed with EEG coherence and phase synchrony analyses. Main findings on EEG coherence in schizophrenic patients at rest and during differen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::11469d56c1e0a7885e60e3b17fe37aac
https://pubmed.ncbi.nlm.nih.gov/23789351

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[Association of the insulin-like growth factor II (IGF2) gene with human cognitive functions]

Autor: M V, Alfimova, T V, Lezheĭko, I K, Gritsenko, V E, Golimbet

Publikováno v: Genetika. 48(8)

Active search for candidate genes whose polymorphisms are associated with human cognitive functions has been in progress in the past years. The study focused on the role that the insulin-like growth factor II (IGF2) gene may play in the variation of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::224c19985f0e220f1ea3d01582c30ba8
https://pubmed.ncbi.nlm.nih.gov/23035551

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