Výsledky vyhledávání - "M V, Savvateeva"

Diagnostic potentials of combined detection of amidolytic activity of hepsin and GSTP1 gene methylation in patients with malignant and other prostate diseases

Autor: Ye. B. Vassileva, A. A. Lyashenko, M. V. Savvateeva, Ye. M. Kuznetsova, S. Ye. Severin, Ye. S. Severin, D. N. Fiyev, Yu. G. Aljaev, A. Z. Vinarov

Publikováno v: Onkourologiâ, Vol 4, Iss 3, Pp 50-53 (2020)

We have assessed the implication of analysis of amydolitic activity of hepsin, which is a trans-membrane serine protease of II type, in the detection of prostate cancer diagnosis. According to literature review over-expression of hepsin is characteri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doajarticles::71be98c2208bc4b6a8cb9d6f7634139e
https://oncourology.abvpress.ru/oncur/article/view/1067

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[Suppression of NR0B2 gene in Clear Cell Renal Cell Carcinoma Is Associated with Hypermethylation of Its Promoter]

Autor: A V, Kudryavtseva, K M, Nyushko, A R, Zaretsky, D A, Shagin, A F, Sadritdinova, M S, Fedorova, M V, Savvateeva, Z G, Guvatova, E A, Pudova, B Y, Alekseev, A A, Dmitriev, A V, Snezhkina

Publikováno v: Molekuliarnaia biologiia. 52(3)

Clear cell renal cell carcinoma (ccRCC) is a common urologic malignancy. Understanding of the transcriptional regulation of oncogenes and tumor suppressor genes involved is critical for the development of the treatments for renal tumors. Using ccRCC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c71c0967b2a136ab061fb09adcfd36dd
https://pubmed.ncbi.nlm.nih.gov/29989580

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Isolation, purification, and study of properties of recombinant hepsin from Escherichia coli

Autor: E. M. Kuznetsova, M. V. Savvateeva, A. A. Raevskaya, S. E. Severin

Publikováno v: Biochemistry (Moscow). 75:866-872

A recombinant hepsin-producing strain of Escherichia coli was obtained and the conditions for hepsin expression in a bacterial system were optimized. To study the physicochemical properties of the enzyme, a procedure for purification of active recomb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5425d765c6521a48197c6f73b862928e
https://doi.org/10.1134/s0006297910070084

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[Murine and human hematopoietic progenitor cultures grown on stromal layers expressing Notch ligands]

Autor: A A, Raevskaya, M V, Savvateeva, S S, Bukhinnik, O F, Kandarakov, P A, Butylin, S V, Zhuk, A M, Demin, V P Krasnov A Y, Zaritsky, A V, Belyavsky

Publikováno v: Molekuliarnaia biologiia. 51(2)

The ex vivo maintenance and expansion of hematopoietic stem cells and early progenitors is necessary for the successful treatment of hematopoietic and immune diseases. Multiple attempts to improve the expansion of hematopoietic stem cells (HSCs) by t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d8ae0eecdf2b21662e1137045cbb18f3
https://pubmed.ncbi.nlm.nih.gov/28537242

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Effect of Anthralin on Cell Viability in Human Prostate Adenocarcinoma

Autor: S. L. Gorbunova, A. A. Raevskaya, S. E. Severin, Mikhail P. Kirpichnikov, M. V. Savvateeva

Publikováno v: Bulletin of Experimental Biology and Medicine. 153:361-363

The study revealed the key role of serine protease hepsin activity in transition of in situ prostate adenocarcinoma into the metastasizing form. Inhibition of hepsin activity suppresses the invasive growth of the tumor. Hepsin is an convenient target

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4727d3a6453e9a5d99b41a3427536821
https://doi.org/10.1007/s10517-012-1716-6

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Disorders in Restructuring of T-Cell Receptor -Chain in Malignant Skin Lymphomas

Autor: M. I. Savina, M. V. Savvateeva, R. T. Toguzov, V. A. Samsonov, L. I. Markusheva

Publikováno v: Bulletin of Experimental Biology and Medicine. 138:179-181

Disorders in restructuring of T-cell receptor gamma-chain in DNA from skin biopsy specimens and peripheral blood lymphocyte of patients with malignant skin lymphomas at different stages of the disease were detected by PCR. Nucleotide sequences of mon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78a8164d83e0ac1eb6b6565d76d121f9
https://doi.org/10.1023/b:bebm.0000048382.03906.32

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Molecular and physiological mechanisms of membrane receptor systems functioning

Autor: E S Severin, M V Savvateeva

Publikováno v: Acta Naturae

Molecular physiology is a new interdisciplinary field of knowledge that looks into how complicated biological systems function. The living cell is a relatively simple, but at the same time very sophisticated biological system. After the sequencing of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f5f1adcef027f2167bd9e7d5651ea28
http://cyberleninka.ru/article/n/molecular-and-physiological-mechanisms-of-membrane-receptor-systems-functioning

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[Determination of the level of antibodies to CD4 in serum of patients with malignant lymphomas and of HIV-infected individuals]

Autor: L F, Lideman, M V, Savvateeva, V M, Stakhanova, L I, Markusheva

Publikováno v: Klinicheskaia laboratornaia diagnostika. (8)

Hardphase ELISA was used to compare the blood sera of patients with malignant skin lymphomas and HIV infection and of healthy volunteers for autoimmune antibodies to CD4. Antibodies to CD4 were not detected in the volunteers (30 sera) and in the pati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::35060d64434a30781367149c263032f9
https://pubmed.ncbi.nlm.nih.gov/15461001

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