Výsledky vyhledávání

Establishment, molecular rescue, and expression of 123AV16-1, a tumor-reactive human monoclonal antibody

Autor: B L, Hall, J H, Murray, M V, Haspel, B J, Kobrin

Publikováno v: Cancer research. 54(19)

The human monoclonal antibody (mAb) 123AV16-1 was generated by Epstein-Barr virus transformation of peripheral blood lymphocytes from a colorectal patient undergoing active specific immunotherapy with an autologous tumor cell-Bacille Calmette-Guérin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::670eecec1e8ba9079d8ea9687f991e2d
https://pubmed.ncbi.nlm.nih.gov/7923137

Zobrazit plný text záznamu

New chelating agent for attaching indium-111 to monoclonal antibodies: in vitro and in vivo evaluation

Autor: Richard P. McCabe, M. V. Haspel, S. Shaban, Michael G. Hanna, H. Sidrak, Nicholas Pomato, R. Subramanian, J. Colony

Publikováno v: Bioconjugate chemistry. 3(3)

111In possesses excellent radiophysical properties suitable for use in immunoscintigraphy of cancerous tissues when attached to an antitumor antibody. However, 111In has a tendency to accumulate in normal tissues such as liver. Instability of the lin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fa494fbaa88b1b1ec082077830741c9
https://pubmed.ncbi.nlm.nih.gov/1520729

Zobrazit plný text záznamu

Recent Developments and Perspectives on the Future of Human and Murine Monoclonal Antibodies in the Diagnosis and Treatment of Cancer

Autor: E. M. Paris, J. A. Carrasquillo, M. G. HannaJr., R. G. Steis, Nicholas Pomato, M. V. Haspel, R. P. McCabe, R. Subramanian

Publikováno v: From Clone to Clinic ISBN: 9789401056830

Over the past 15 years there has been a substantial effort to develop the potential of monoclonal antibody technology into medical applications. Significant progress has been made, especially in in vitro applications where the superiority of monoclon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::db902625489f96e2776b7d06e5f73130
https://doi.org/10.1007/978-94-011-3780-5_21

Zobrazit plný text záznamu

Natural cytotoxicity against mouse hepatitis virus-infected target cells. I. Correlation of cytotoxicity with virus binding to leukocytes

Autor: K V Holmes, R M Welsh, M V Haspel

Publikováno v: The Journal of Immunology. 136:1446-1453

Spleen cells from uninfected control mice selectively lysed BALB/c 3T3 fibroblasts infected with mouse hepatitis virus (MHV), a murine coronavirus. Lysis of infected cells occurred within 3 hr, and histocompatibility between effector and target cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3a5c0cf8eb2115919f290c073c4a5cf8
https://doi.org/10.4049/jimmunol.136.4.1446

Zobrazit plný text záznamu

Genetic analysis of murine hepatitis virus strain JHM

Autor: M V Haspel, Julian L. Leibowitz, James R. Devries

Publikováno v: Journal of Virology. 42:1080-1087

We performed a genetic analysis of 37 temperature-sensitive mutants of murine hepatitis virus strain JHM. Of our mutants, 32 did not induce murine hepatitis virus-specific RNA synthesis in infected cells at the restrictive temperature, 39 degrees C.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::685329b5024fbb3590b836d2fdd2d2d4
https://doi.org/10.1128/jvi.42.3.1080-1087.1982

Zobrazit plný text záznamu

Natural cytotoxicity against mouse hepatitis virus-infected cells. II. A cytotoxic effector cell with a B lymphocyte phenotype

Autor: R M, Welsh, M V, Haspel, D C, Parker, K V, Holmes

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 136(4)

The effector cell in mouse spleen which mediates natural cytotoxicity against mouse hepatitis virus (MHV)-infected target cells was characterized. The target cells were MHV-infected BALB/c 3T3, and the assay time was 3 hr. The effector cell, designat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::756ef1b3deb9fdf583831a520119c9af
https://pubmed.ncbi.nlm.nih.gov/3003199

Zobrazit plný text záznamu

Natural cytotoxicity against mouse hepatitis virus-infected target cells. I. Correlation of cytotoxicity with virus binding to leukocytes

Autor: K V, Holmes, R M, Welsh, M V, Haspel

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 136(4)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c8f368d8360ba8be2cc42c6e80e99d30
https://pubmed.ncbi.nlm.nih.gov/3003198

Zobrazit plný text záznamu

Preclinical studies on the pharmacokinetic properties of human monoclonal antibodies to colorectal cancer and their use for detection of tumors

Autor: R P, McCabe, L C, Peters, M V, Haspel, N, Pomato, J A, Carrasquillo, M G, Hanna

Publikováno v: Cancer research. 48(15)

We studied the pharmacokinetic properties of two human monoclonal antibodies to colon carcinoma cells and their ability to detect tumors in nude mice bearing primary human colon carcinoma xenografts. The 16-88 and 28A32 monoclonal antibodies are immu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cf4974a2cf02806e0c6b57b9a4ca249d
https://pubmed.ncbi.nlm.nih.gov/3390831

Zobrazit plný text záznamu

Acute and Recurrent Demyelination Induced by Wild-Type and Temperature-Sensitive Mutants of Mouse Hepatitis Virus. Electron-Microscopic Studies

Autor: Michael B. A. Oldstone, Peter W. Lampert, M. V. Haspel

Publikováno v: Progress in Multiple Sclerosis Research ISBN: 9783642675560

Weanling mice infected with the neurotropic JHM strain of mouse hepatitis virus (MHV), a coronavirus, develop an acute demyelinating encephalomyelitis [1]. Demyelination occurs as a result of virus-induced destruction of oligodendrocytes [6]. The sev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d8f559a53d2109e61827200fadeea807
https://doi.org/10.1007/978-3-642-67554-6_6

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání