Zobrazeno 1 - 6
of 6
pro vyhledávání: '"M V, González Meana"'
Autor:
J P, Rodrigo Tapia, F, Domínguez Iglesias, C, Alvarez Marcos, M V, González Meana, J, García Pedrero, C, Suárez Nieto
Publikováno v:
Acta otorrinolaringologica espanola. 55(10)
The E-cadherin adhesion molecule is fundamentally involved in the maintenance of normal epithelial morphology and differentiation. The scattering and invasion of cancer cells induced by epidermal growth factor receptor (EGFR) activation has been sugg
Autor:
G, Sequeiros Santiago, J P, Rodrigo Tapia, D, García-Carracedo, J, García Pedrero, C, Suárez Nieto, M V, González Meana
Publikováno v:
Acta otorrinolaringologica espanola. 55(2)
Adenoid cystic carcinoma (ACC) is a tumour of epithelial origin that represents the most common malignant neoplasm of the minor salivary glands. However, little is known about the genes involved in the development and progression of this tumour. Cycl
Autor:
J P, Rodrigo Tapia, F, Domínguez Iglesias, C, Alvarez Marcos, M V, González Meana, J, García Pedrero, C, Suárez Nieto
Publikováno v:
Acta otorrinolaringologica espanola. 53(10)
To establish the prognostic significance of the expression of adhesion molecules E-cadherin, CD44s and CD44v6 in squamous cell carcinomas of the supraglottic larynx.The expression of the studied molecules was determined by immunohistochemistry in par
Autor:
J P, Rodrigo Tapia, M V, González Meana, L A, García González, E, Coto, J, García Pedrero, F, Núñez Batalla, C, Suárez Nieto
Publikováno v:
Acta otorrinolaringologica espanola. 53(4)
P53 and CCND1 (cyclin D1) genes play a critical role in the cell cycle regulation. Abnormalities of these genes are frequent in different types of cancers, including those of the head and neck. The aim of this work is to investigate whether P53 inact
Autor:
A, Martínez Ferreras, J P, Rodrigo Tapia, M V, González Meana, I, Alvarez Alvarez, E, Coto, C, Suárez Nieto
Publikováno v:
Acta otorrinolaringologica espanola. 52(7)
Human papillomavirus integration in cellular DNA and loss of heterozygosity of P53 gene are both related with tumour formation process by promoting genomic instability that leads to DNA abnormalities accumulation. In order to analyze the relationship
Autor:
J P, Rodrigo Tapia, L A, García González, J A, Martínez Sánchez, M V, González Meana, J M, García Pedrero, C, Suárez Nieto
Publikováno v:
Acta otorrinolaringologica espanola. 52(7)
Cyclin D1 protein (encoded by the CCND1 gene) contributes to the progression of the cell cycle in the G1/S checkpoint. Cyclin D1 overexpression (for instance as a consequence of CCND1 amplification) might result in loss of control over genetic damage