Zobrazeno 1 - 10
of 16
pro vyhledávání: '"M V, Donova"'
Autor:
M. V. Karpov, V. M. Nikolaeva, V. V. Fokina, A. A. Shutov, A. V. Kazantsev, N. I. Strizhov, M. V. Donova
Publikováno v:
Applied Biochemistry and Microbiology. 58:947-957
Publikováno v:
Microbiology. 91:303-312
Autor:
V. Yu. Poshekhontseva, V. V. Fokina, S. V. Tarlachkov, A. V. Machulin, A. A. Shutov, M. V. Donova
Publikováno v:
Applied Biochemistry and Microbiology
The Streptomyces sp. VKM Ac-2618D strain has been identified, and its morphological and physiological features have been studied in relation to the production of the immunosuppressant tacrolimus. The phenotypic variability of the strain was analyzed,
Publikováno v:
Прикладная биохимия и микробиология. 51:174-182
The transformation of dehydroepiandrosterone by Spicaria fumoso-rosea VKM F-881 produced 7alpha- and 7beta-hydroxy-dehydroepiandrosterone, 3beta,7alpha-dihydroxy-17a-oxa-D-homo-androst-5-en-17-one, and 3beta,7beta-dihydroxy- 17a-oxa-D-homo-androst-5-
Publikováno v:
Prikladnaia biokhimiia i mikrobiologiia. 51(2)
Selected filamentous fungi--98 strains of 31 genera--were screened for the ability to catalyze 11beta-hydroxylation of 6alpha-fluoro-16alpha-methyl-deoxycorticosterone 21-acetate (FM-DCA). It was established that representatives of the genera Gongron
Publikováno v:
Prikladnaia biokhimiia i mikrobiologiia. 46(2)
Regio- and stereospecificity of microbial hydroxylation was studied at the transformation of 3-keto-4-ene steroids of androstane and pregnane series by the filamentous fungus of Curvularia lunata VKMF-644. The products of the transformations were iso
Publikováno v:
Prikladnaia biokhimiia i mikrobiologiia. 45(6)
The ability of 485 fungal strains is studied for catalysis of the process of 7alpha, 15alpha-dihydroxylation of dehydroepiandrosterone (DHEA, 3alpha-hydroxy-5-androstene-17-one), a key intermediate of the synthesis of physiologically active compounds
Autor:
M V, Donova
Publikováno v:
Prikladnaia biokhimiia i mikrobiologiia. 43(1)
Development of pharmaceutical industry is currently aimed at introducing biotechnological processes on a large-scale and thereby replacing multiple-stage chemical syntheses. Actinobacteria are efficient biocatalysts of many processes involving steroi
Publikováno v:
Prikladnaia biokhimiia i mikrobiologiia. 41(5)
The key enzymes involved in modification of the steroid nucleus of sterol-transforming mycobacteria--3beta-hydroxysteroid oxidase (3-OH-SO, EC 1.13.1.2) and 17beta-hydroxysteroid dehydrogenase (17-OH-SDH, EC 1.1.1)--were isolated and characterized. I
Autor:
V V, Fokina, G V, Sukhodol'skaia, S A, Gulevskaia, E Iu, Gavrish, L I, Evtushenko, M V, Donova
Publikováno v:
Mikrobiologiia. 72(1)
The bacterium formerly known as Arthrobacter globiformis 193 has high 1(2)-dehydrogenase activity toward pharmaceutically important steroids, 9(11)-dehydrocortexolone in particular. The complex analysis of the morphostructural, physiological, biochem