Zobrazeno 1 - 10
of 41
pro vyhledávání: '"M Ujue Latasa"'
Autor:
Carla Rojo, María Gárate-Rascón, Miriam Recalde, Ane Álava, María Elizalde, María Azkona, Iratxe Aldabe, Elisabet Guruceaga, Amaya López-Pascual, M Ujue Latasa, Bruno Sangro, Maite G. Fernández-Barrena, Matías A. Ávila, María Arechederra, Carmen Berasain
Publikováno v:
JHEP Reports, Vol 6, Iss 8, Pp 101118- (2024)
Background & Aims: The homeostasis of the cellular transcriptome depends on transcription and splicing mechanisms. Moreover, the fidelity of gene expression, essential to preserve cellular identity and function is secured by different quality control
Externí odkaz:
https://doaj.org/article/839678c118424464b7ef2ce1b0908674
Autor:
M Ujue Latasa, Carmen Gil-Puig, Maite G Fernández-Barrena, Carlos M Rodríguez-Ortigosa, Jesús M Banales, Raquel Urtasun, Saioa Goñi, Miriam Méndez, Sara Arcelus, Nerea Juanarena, Juan A Recio, Sophie Lotersztajn, Jesús Prieto, Carmen Berasain, Fernando J Corrales, Jon Lecanda, Matías A Avila
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15690 (2010)
BackgroundInflammation and fibrogenesis are directly related to chronic liver disease progression, including hepatocellular carcinoma (HCC) development. Currently there are few therapeutic options available to inhibit liver fibrosis. We have evaluate
Externí odkaz:
https://doaj.org/article/ea72f5c5f43e4344b69e60e69b24e059
Autor:
Leticia Colyn, Gloria Alvarez-Sola, M. Ujue Latasa, Iker Uriarte, Jose M. Herranz, Maria Arechederra, George Vlachogiannis, Colin Rae, Antonio Pineda-Lucena, Andrea Casadei-Gardini, Federica Pedica, Luca Aldrighetti, Angeles López-López, Angeles López-Gonzálvez, Coral Barbas, Sergio Ciordia, Sebastiaan M. Van Liempd, Juan M. Falcón-Pérez, Jesus Urman, Bruno Sangro, Silve Vicent, Maria J. Iraburu, Felipe Prosper, Leonard J. Nelson, Jesus M. Banales, Maria Luz Martinez-Chantar, Jose J. G. Marin, Chiara Braconi, Christian Trautwein, Fernando J. Corrales, F. Javier Cubero, Carmen Berasain, Maite G. Fernandez-Barrena, Matias A. Avila
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-18 (2022)
Abstract Background Cholangiocarcinoma (CCA) is still a deadly tumour. Histological and molecular aspects of thioacetamide (TAA)-induced intrahepatic CCA (iCCA) in rats mimic those of human iCCA. Carcinogenic changes and therapeutic vulnerabilities i
Externí odkaz:
https://doaj.org/article/278c7dac66c24c988487ac905912005b
Autor:
Carmen Berasain, Matías A. Avila, Jesús Prieto, Bruno Sangro, Victor Segura, Saioa Goñi, M. Ujue Latasa, Josefa Castillo, Maria J. Perugorria
Supplementary Table 1 from Wilms' Tumor 1 Gene Expression in Hepatocellular Carcinoma Promotes Cell Dedifferentiation and Resistance to Chemotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e0a5239d8d8c7884be76d5caf534ae4
https://doi.org/10.1158/0008-5472.22380801
https://doi.org/10.1158/0008-5472.22380801
Autor:
Carmen Berasain, Matías A. Avila, Jesús Prieto, Bruno Sangro, Victor Segura, Saioa Goñi, M. Ujue Latasa, Josefa Castillo, Maria J. Perugorria
The Wilms' tumor 1 gene (WT1) encodes a transcription factor involved in cell growth and development. As we previously reported, WT1 expression is hardly detectable in normal hepatic tissue but is induced in liver cirrhosis. Although WT1 has been fou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab463b69303a79746c346f23f6c32c23
https://doi.org/10.1158/0008-5472.c.6499680.v1
https://doi.org/10.1158/0008-5472.c.6499680.v1
Autor:
Carmen Berasain, María Azkona, Bruno Sangro, Matías A. Avila, María Gárate-Rascón, María Angeles Sotés Elizalde, M. Ujue Latasa, Maite G. Fernandez-Barrena, Marina Bárcena-Varela, Miriam Recalde, María Arechederra
Publikováno v:
Nucleic Acids Research
Gene expression is finely and dynamically controlled through the tightly coordinated and interconnected activity of epigenetic modulators, transcription and splicing factors and post-translational modifiers. We have recently identified the splicing f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94e8625243dc98d33675cf26ffda3e2a
http://europepmc.org/articles/PMC8421144
http://europepmc.org/articles/PMC8421144
Autor:
Julen Oyarzabal, Robert Arnes-Benito, Leticia Colyn, Jose J.G. Marin, Jose M Herranz, Maite G. Fernandez-Barrena, María J. Iraburu, Maria Francesconi, Gloria Alvarez-Sola, Meritxell Huch, Leonard J Nelson, Francisco Javier Cubero, Matías A. Avila, Altaf A. Dar, Jesus M. Banales, Iker Uriarte, Mikel Ruiz de Gauna, Simone Carotti, Jesús Urman, Sergio Morini, María L. Martínez-Chantar, Chaobo Chen, Marina Bárcena-Varela, Eva Santamaría, Andrea Casadei-Gardini, Christian Trautwein, Patricia Aspichueta, Alvaro Santos-Laso, Carmen Berasain, Felipe Prosper, Bruno Sangro, John M Patino, Matteo Canale, Mehdi Nosrati, María Arechederra, M. Ujue Latasa
Publikováno v:
Hepatology. 73:2380-2396
Background and aims Cholangiocarcinoma (CCA) is a devastating disease often detected at advanced stages when surgery cannot be performed. Conventional and targeted systemic therapies perform poorly, and therefore effective drugs are urgently needed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a81ae64ca991d1997b859d84eab9eef5
https://doi.org/10.1002/hep.31642
https://doi.org/10.1002/hep.31642
Autor:
Cristina Saldaña, Iranzu González-Borja, David Guerrero-Setas, Ignacio Fernandez-Urien, María Angeles Sotés Elizalde, Jose M Herranz, Waldemar Patkowski, Francisco Javier Cubero, Irene Amat, Ana Purroy, María Rullán, Daniel Oyón, Gorka Alkorta-Aranburu, Carmen Berasain, Krzysztof Zieniewicz, Marcin Krawczyk, Lucía Zabalza, Juan J. Vila, Matías A. Avila, Piotr Milkiewicz, Leonard J Nelson, Maria Del Rosario Mercado, Vanesa Jusué, D. Ruiz-Clavijo, M. Ujue Latasa, Isabel Gil, Maite G. Fernandez-Barrena, Cruz Zazpe, María Arechederra, Bruno Sangro, Jesús Urman, Juan Carrascosa
Publikováno v:
Academica-e. Repositorio Institucional de la Universidad Pública de Navarra
instname
instname
Objective: despite significant progresses in imaging and pathological evaluation, early differentiation between benign and malignant biliary strictures remains challenging. Endoscopic retrograde cholangiopancreatography (ERCP) is used to investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2176e8557a33f165616e0a9d39f6068
https://pubmed.ncbi.nlm.nih.gov/34285068
https://pubmed.ncbi.nlm.nih.gov/34285068
Autor:
Matías A. Avila, Giuseppe Perrone, Leticia Colyn, Claudia Bagni, Rocco Simone Flammia, Maite G. Fernandez-Barrena, Maria Francesconi, Laura D’Andrea, Sergio Morini, Maria Zingariello, Daniela Righi, M. Ujue Latasa, Francesca Zalfa, Francesco Pantano, Giorgia Pedini, Mario Falchi, Rosa Alba Rana, Simone Carotti
Publikováno v:
Oncogene
Intrahepatic cholangiocarcinoma (iCCA) is a rare malignancy of the intrahepatic biliary tract with a very poor prognosis. Although some clinicopathological parameters can be prognostic factors for iCCA, the molecular prognostic markers and potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::878fc54fa49f5d5ec568c7f95598a657
http://hdl.handle.net/11573/1639473
http://hdl.handle.net/11573/1639473
Autor:
Raquel Urtasun, Maite G. Fernandez-Barrena, María Azkona, Maddalen Jimenez, Bruno Sangro, Iker Uriarte, Eva Santamaría, C.M. Rodriguez-Ortigosa, María Arechederra, Marina Bárcena-Varela, Diego Alignani, Matías A. Avila, Carmen Berasain, M.R. Elizalde, Leticia Colyn, Gloria Alvarez-Sola, M. Ujue Latasa
Publikováno v:
Nucleic Acids Research
Genome instability is related to disease development and carcinogenesis. DNA lesions are caused by genotoxic compounds but also by the dysregulation of fundamental processes like transcription, DNA replication and mitosis. Recent evidence indicates t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3e93dd82cbf6ddea1af1f1a4ea764da
https://pubmed.ncbi.nlm.nih.gov/30657957
https://pubmed.ncbi.nlm.nih.gov/30657957