Zobrazeno 1 - 10
of 622
pro vyhledávání: '"M Timmer"'
Autor:
N Roescher, JM Prins, JTM van der Meer, HI Bax, R Soetekouw, MGJ de Boer, LBS Gelinck, JJ Oosterheert, MA van Agtmael, M Berrevoets, DTP Buis, CH van Werkhoven, MJM Bonten, JE Bosmans, J Branger, S Douiyeb, E Jong, AJJ Lammers, E Sieswerda, JE Stalenhoef, TW Van der Vaart, EA Bij de Vaate, NJ Verkaik, MGA Van Vonderen, PJ De Vries, KCE Sigaloff, E Botman, A Van den Broek, L Buitenhuis, E Buitenwerf, A S Cents, N Engels, J L J Hanssen, A J Meinders, F P N Mollema, L Nagelmaker, M L M van Doorn-Schepens, P Thomopoulos, M Timmer, B van der Wiel
Publikováno v:
BMJ Open, Vol 13, Iss 4 (2023)
Introduction A major knowledge gap in the treatment of complicated Staphylococcus aureus bacteraemia (SAB) is the optimal duration of antibiotic therapy. Safe shortening of antibiotic therapy has the potential to reduce adverse drug events, length of
Externí odkaz:
https://doaj.org/article/cf2fa20a75a4412a9dbd8b21a6ce2c68
Publikováno v:
Gastro Hep Advances, Vol 2, Iss 1, Pp 63-71 (2023)
Background and Aims: Barrett's esophagus (BE) is the precursor lesion for esophageal adenocarcinoma (EAC). To detect EAC in early stage, patients with BE undergo endoscopic surveillance. Surveillance cohorts largely consist of nondysplastic BE (NDBE)
Externí odkaz:
https://doaj.org/article/563805a5ea2341f2a536fad0b654e164
Autor:
Thathsaranie P. Manthrirathna, M.A., Kodar, Kristel, Ishizuka, Shigenari, Dangerfield, Emma M., Xiuyuan, Lu, Yamasaki, Sho, Stocker, Bridget L., S. M. Timmer, Mattie
Publikováno v:
In Bioorganic Chemistry April 2023 133
Autor:
Tim M. Hoogstad, Stijn M. Timmer, Dr. Anton J. B. vanBoxtel, Dr. Pieter L. Buwalda, Prof. Dr. Johannes H. Bitter, Dr. Lars Kiewidt
Publikováno v:
ChemistryOpen, Vol 11, Iss 10, Pp n/a-n/a (2022)
Abstract Oxidised starch is currently produced from native starch using sodium hypochlorite as an oxidising agent. The use of hypochlorite has undesired side reactions and produces stoichiometric amounts of waste (salt), thus alternative oxidation me
Externí odkaz:
https://doaj.org/article/12a8a62396ee4bcb8112217bb152b139
Publikováno v:
Computational Psychiatry, Vol 2, Pp 11-27 (2018)
Patients with Parkinson’s disease (PD) are often treated with dopaminergic medication. Dopaminergic medication is known to improve both motor and certain nonmotor symptoms, such as depression. However, it can contribute to behavioral impairment, fo
Externí odkaz:
https://doaj.org/article/9e037f2ef0e4418cabe0e5c7c875f6e5
Autor:
Kristel Kodar, Emma M. Dangerfield, Amy J. Foster, Devlin Forsythe, Shigenari Ishizuka, Melanie J. McConnell, Sho Yamasaki, Mattie S. M. Timmer, Bridget L. Stocker
Publikováno v:
Inflammation.
Abstract—α,α′-Trehalose 6,6′-glycolipids have long been known for their immunostimulatory properties. The adjuvanticity of α,α′-trehalose 6,6′-glycolipids is mediated by signalling through the macrophage inducible C-type lectin (Mincle)
Akademický článek
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Akademický článek
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Autor:
Garth Cameron, Janice M. H. Cheng, Dale I. Godfrey, Mattie S. M. Timmer, Bridget L. Stocker, Emma M. Dangerfield
Publikováno v:
RSC Advances. 12:18493-18500
Isoglobotrihexosylceramide (iGb3) is a known NKT cell agonist, however the specific interactions required to trigger NKT cell TCR activation in response to this mammalian glycolipid are not fully understood. Here we report the synthesis of 1,3-β-Gal
Autor:
Chriselle D. Braganza, Kristel Kodar, Thomas Teunissen, Sarah K. Andreassend, Ayesha Khan, Mattie S. M. Timmer, Bridget L. Stocker
Publikováno v:
Organic & Biomolecular Chemistry. 20:3096-3104
Macrophage inducible C-type lectin (Mincle) is a pattern recognition receptor on myeloid cells that represents a promising target for Th1-stimulating adjuvants. We report on the synthesis of branched and aromatic glucose monoesters and glycosides and