Zobrazeno 1 - 10
of 155
pro vyhledávání: '"M Teresa Pisabarro"'
Autor:
Claudia Damaris Müller, Gloria Ruiz-Gómez, Sophie Cazzonelli, Stephanie Möller, Robert Wodtke, Reik Löser, Joanna Freyse, Jan-Niklas Dürig, Jörg Rademann, Ute Hempel, M. Teresa Pisabarro, Sarah Vogel
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Transglutaminases (TGs) catalyze the covalent crosslinking of proteins via isopeptide bonds. The most prominent isoform, TG2, is associated with physiological processes such as extracellular matrix (ECM) stabilization and plays a crucial rol
Externí odkaz:
https://doaj.org/article/ec1ce90abb794cc0b3ccdc64ff3a478e
Autor:
Carla Guillén-Pingarrón, Pedro M. Guillem-Gloria, Anjali Soni, Gloria Ruiz-Gómez, Martina Augsburg, Frank Buchholz, Massimiliano Anselmi, M. Teresa Pisabarro
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 989-1001 (2022)
Protein intrinsically disordered regions (IDRs) play pivotal roles in molecular recognition and regulatory processes through structural disorder-to-order transitions. To understand and exploit the distinctive functional implications of IDRs and to un
Externí odkaz:
https://doaj.org/article/67284fa5206f417cb15625c7550bf64d
Publikováno v:
ACS Omega, Vol 6, Iss 39, Pp 25350-25360 (2021)
Externí odkaz:
https://doaj.org/article/b53c74e74f104fe391fdb87cb45a4d76
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract The tyrosine-type site-specific DNA recombinase Cre recombines its target site, loxP, with high activity and specificity without cross-recombining the target sites of highly related recombinases. Understanding how Cre achieves this precision
Externí odkaz:
https://doaj.org/article/5dbe91c778ae4be9a00457b7e08a610c
Autor:
Claudia Damaris Müller, Gloria Ruiz-Gómez, Sophie Cazzonelli, Stephanie Möller, Robert Wodtke, Reik Löser, Joanna Freyse, Jan-Niklas Dürig, Jörg Rademann, Ute Hempel, M. Teresa Pisabarro, Sarah Vogel
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/3a52a3cf3ee5429eb426bbaf548003d3
Autor:
Linda Koehler, Sergey Samsonov, Sandra Rother, Sarah Vogel, Sebastian Köhling, Stephanie Moeller, Matthias Schnabelrauch, Jörg Rademann, Ute Hempel, M. Teresa Pisabarro, Dieter Scharnweber, Vera Hintze
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Glycosaminoglycans are known to bind biological mediators thereby modulating their biological activity. Sulfated hyaluronans (sHA) were reported to strongly interact with transforming growth factor (TGF)-β1 leading to impaired bioactivity i
Externí odkaz:
https://doaj.org/article/c04d4419433f40119e66c264da1ea33c
Autor:
Lydia Behring, Gloria Ruiz-Gómez, Christian Trapp, Maryann Morales, Robert Wodtke, Martin Köckerling, Klaus Kopka, M. Teresa Pisabarro, Jens Pietzsch, Reik Löser
Publikováno v:
Journal of Medicinal Chemistry 66(2023)6, 3818-3851
The potential of designing irreversible alkyne-based inhibitors of cysteine cathepsins by isoelectronic replacement in reversibly acting potent peptide nitriles was explored. The synthesis of the dipeptide alkynes was developed with special emphasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3e6b75e449be17aa95c9a35b6eea79b
https://www.hzdr.de/publications/Publ-35046-1
https://www.hzdr.de/publications/Publ-35046-1
Autor:
Gloria Ruiz-Gómez, Juliane Salbach-Hirsch, Jan-Niklas Dürig, Linda Köhler, Kanagasabai Balamurugan, Sandra Rother, Sophie-Luise Heidig, Stephanie Moeller, Matthias Schnabelrauch, Giulia Furesi, Sophie Pählig, Pedro M. Guillem-Gloria, Christine Hofbauer, Vera Hintze, M. Teresa Pisabarro, Jörg Rademann, Lorenz C. Hofbauer
Publikováno v:
Biomaterials. 297:122105
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::127d09c3faa1b16e0d72618d31a65866
https://doi.org/10.1016/j.biomaterials.2023.122105
https://doi.org/10.1016/j.biomaterials.2023.122105
Autor:
Linda Koehler, Gloria Ruiz-Gómez, Karen M. Fiebig, Johannes Waltenberger, Matthias Schnabelrauch, Dieter Scharnweber, Kanagasabai Balamurugan, M. Teresa Pisabarro, Vera Hintze, Vanessa D. Galiazzo, Sandra Rother, Stephanie Moeller, Ute Hempel
Publikováno v:
ACS Applied Bio Materials. 4:494-506
In order to restore the regeneration capacity of large-size vascularized tissue defects, innovative biomaterial concepts are required. Vascular endothelial growth factor (VEGF165) is a key factor o...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83485cd338f617704cdd99248ec1c44f
https://doi.org/10.1021/acsabm.0c01001
https://doi.org/10.1021/acsabm.0c01001
Autor:
Gloria Ruiz-Gómez, John C Hawkins, Jenny Philipp, Georg Künze, Robert Wodtke, Reik Löser, Karim Fahmy, M Teresa Pisabarro
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0154046 (2016)
Tackling protein interfaces with small molecules capable of modulating protein-protein interactions remains a challenge in structure-based ligand design. Particularly arduous are cases in which the epitopes involved in molecular recognition have a no
Externí odkaz:
https://doaj.org/article/6c75ecc614f94652adbdc16933160916