Identification of BiP as a CB1 receptor-interacting protein that fine-tunes cannabinoid signaling in the mouse brain

Autor: David Martín-Gutiérrez, Ignacio Rodríguez-Crespo, Giovanni Marsicano, Joaquin Botta, Leyre Urigüen, José Sánchez-Prieto, Marc Espina, Rebeca Diez-Alarcia, Irene B. Maroto, Carlos Costas-Insua, Nuria García-Font, Raquel Bajo-Grañeras, Peter J. McCormick, Roser Cortés, Vicent Casadó, Andrea Ruiz-Calvo, Manuel Guzmán, Enric I. Canela, M. Teresa Vilaró, Ismael Galve-Roperh, Estefanía Moreno, Silvia Ginés, Guadalupe Mengod, Luigi Bellocchio, Ricardo Martín

Publikováno v: Journal of Neuroscience
Journal of Neuroscience, Society for Neuroscience, 2021, 41 (38), pp.7924-7941. ⟨10.1523/JNEUROSCI.0821-21.2021⟩
Addi. Archivo Digital para la Docencia y la Investigación
instname
Digital.CSIC. Repositorio Institucional del CSIC
Dipòsit Digital de la UB
Universidad de Barcelona

Cannabinoids, the bioactive constituents of cannabis, exert a wide array of effects on the brain by engaging Type 1 cannabinoid receptor (CB1R). Accruing evidence supports that cannabinoid action relies on context-dependent factors, such as the biolo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c37fb9bb32a834bae66d420b7820be79
http://hdl.handle.net/2445/181159

Visualization of 5-HT Receptors Using Radioligand-Binding Autoradiography

Autor: M. Teresa Vilaró, Guadalupe Mengod, Roser Cortés

Publikováno v: Current Protocols in Pharmacology

Described in this unit are techniques to visualize the majority of serotonin (5-hydroxytryptamine, 5-HT) receptor subtypes in sections of frozen brain tissue using receptor autoradiography. Protocols for brain extraction and sectioning, radioligand e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b697765e763a562b014d3d6f3d7b5288
https://pubmed.ncbi.nlm.nih.gov/27960027

Serotonin 5-HT4receptors and their mRNAs in rat and guinea pig brain: Distribution and effects of neurotoxic lesions

Autor: Roser Cortés, M. Teresa Vilaró, Guadalupe Mengod

Publikováno v: Journal of Comparative Neurology. 484:418-439

Serotonin 5-HT4 receptors are widely distributed in the periphery and in brain, where they modulate the release of various neurotransmitters and have been implicated in learning and memory. Nine C-terminal splice variants of this receptor have been c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2e81cc94df3fb831f4ea2d5bad41ba9c
https://doi.org/10.1002/cne.20447

5-ht5BReceptor mRNA in the raphe nuclei: Coexpression with serotonin transporter

Autor: Jordi Serrats, Guadalupe Mengod, M. Teresa Vilaró, Roser Cortés, Andreu Raurich

Publikováno v: Synapse. 51:102-111

Contract grant sponsor: >Ministerio de Ciencia y Tecnologia> (MCYT); Contract grant numbers: SAF97-0117, SAF2000-0212; Contract grant sponsor: DURSI - >Generalitat de Catalunya> to the Department of Neurochemistry of IIBB-CSIC (IDIBAPS) as a >Grup de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8526e710e51677adb25778517a9dc13c
https://doi.org/10.1002/syn.10287

Regional distribution and cellular localization of 5-HT2Creceptor mRNA in monkey brain: Comparison with [3H]mesulergine binding sites and choline acetyltransferase mRNA

Autor: José Palacios, M. Teresa Vilaró, Juan F. López-Giménez, Guadalupe Mengod

Publikováno v: Synapse. 42:12-26

The distribution of serotonin 5-HT(2C) receptor mRNA in monkey brain was studied by in situ hybridization and compared with the distribution of [3H]mesulergine binding sites as visualized by receptor autoradiography. 5-HT(2C) receptor transcripts sho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::71ff3ed8096a4dee59f295c65d970ef8
https://doi.org/10.1002/syn.1095