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Atractylodis Rhizoma extract and its component, atractylon, inhibit tumor promotion in mouse skin two-stage carcinogenesis

Autor: S. Yu, K. Yasukawa, M. Takido

Publikováno v: Phytomedicine : international journal of phytotherapy and phytopharmacology. 1(1)

Summary The methanol extract of Atractylodis Rhizoma, a traditional Chinese medicine, was found to have antitumor-promoting activity in two-stage carcinogenesis. From the active fraction of the extract, atractylon was isolated. The isolated compound

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fc2719b8c381cf979384b5806e884ca
https://pubmed.ncbi.nlm.nih.gov/23195816

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Inhibitory effects of sterols isolated from Chlorella vulgaris on 12-0-tetradecanoylphorbol-13-acetate-induced inflammation and tumor promotion in mouse skin

Autor: K, Yasukawa, T, Akihisa, H, Kanno, T, Kaminaga, M, Izumida, T, Sakoh, T, Tamura, M, Takido

Publikováno v: Biologicalpharmaceutical bulletin. 19(4)

Inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice was observed in the methanol extract of Chlorella vulgaris, a green alga. The hexane soluble fraction obtained from the methanol extract exhibited mar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b2cd8fdf506ed47543c40725368d20c1
https://pubmed.ncbi.nlm.nih.gov/8860961

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Sterol and triterpene derivatives from plants inhibit the effects of a tumor promoter, and sitosterol and betulinic acid inhibit tumor formation in mouse skin two-stage carcinogenesis

Autor: Ken Yasukawa, M Takido, Shigeki Nakagawa, T Matsumoto, Mieko Takeuchi

Publikováno v: Oncology. 48(1)

A single topical application of 1 microgram of 12-O-tetradecanoylphorbol- 13-acetate (TPA) to the ears of mice was shown to induce edema, and this TPA-induced inflammation was inhibited by 4-methylsterol and triterpene derivatives. The ED50 of these

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::768d96af53b5350af3aaeb6fab69cf25
https://pubmed.ncbi.nlm.nih.gov/1898988

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Effects of 12-sulfodehydroabietic acid monosodium salt (TA-2711), a new anti-ulcer agent, on gastric mucosal lesions induced by necrotizing agents and gastric mucosal defensive factors in rats

Autor: Y, Onoda, M, Takido, T, Magaribuchi, H, Tamaki

Publikováno v: Japanese journal of pharmacology. 52(4)

Effects of TA-2711 on gastric mucosal lesions induced by various necrotizing agents and several defensive factors of gastric mucosa were investigated in rats. Oral administration of TA-2711 at 12.5 to 200 mg/kg prevented the formation of gastric muco

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6274cc06b5d8cb63fb4d608a9cdb341c
https://pubmed.ncbi.nlm.nih.gov/2342230

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Biosynthesis of phenolic tetrahydroisoquinoline alkaloids of peyote

Autor: H. Rosenberg, M. Takido, A.G. Paul, K. L. Khanna

Publikováno v: Phytochemistry. 9:1811-1815

Data are presented supporting a proposed pathway of biosynthesis of the phenolic tetrahydroisoquinoline alkaloids of peyote from dopamine. It is suggested that meta - O -methylation of dopamine, hydroxylation in the 5-position, para - O -methylation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f8c968292e5ff8acd8e403beda23c5c8
https://doi.org/10.1016/s0031-9422(00)85597-1

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