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Autor:
Ruud A. W. Veldhuizen, Xiujun Jiao, Yi Y. Zuo, Fred Possmayer, Seyed M. Tadayyon, Eleonora Keating
Publikováno v:
Biophysical Chemistry. 158:119-125
Pulmonary surfactant facilitates breathing by forming a surface tension reducing film at the air–liquid interface of the alveoli. The objective was to characterize the structure of surfactant films using endogenous rat surfactant. Solid-support sur
Publikováno v:
Particuology. 8:400-406
An interfacial force microscope (IFM) was employed to measure the inter-particle forces between two individual glass beads with diameters varying from 8 to 20 μm. With the feedback function of IFM turned off, attractive forces were obtained. The for
Publikováno v:
IEEE Transactions on Nanotechnology. 9:487-493
The minimization of sources of uncertainty in nanoindentation experiments is crucial for accurate determination of nanomechanical properties. A common source of uncertainty in these measurements is the estimation of tip shape and size. Besides the ex
Autor:
Matthias Amrein, Yi Y. Zuo, Ruud A. W. Veldhuizen, Lin Zhao, Nils O. Petersen, Eleonora Keating, Seyed M. Tadayyon, Fred Possmayer
Publikováno v:
Biophysical Journal. 95:2779-2791
Pulmonary surfactant (PS) dysfunction because of the leakage of serum proteins into the alveolar space could be an operative pathogenesis in acute respiratory distress syndrome. Albumin-inhibited PS is a commonly used in vitro model for studying surf
Autor:
Seyed M. Tadayyon, Eleonora Keating, Nils O. Petersen, Fred Possmayer, Lin Zhao, Yi Y. Zuo, Ruud A. W. Veldhuizen
Publikováno v:
Biophysical Journal. 94:3549-3564
Monolayers of a functional pulmonary surfactant (PS) can reach very low surface tensions well below their equilibrium value. The mechanism by which PS monolayers reach such low surface tensions and maintain film stability remains unknown. As shown pr
Autor:
Peter R. Norton, Weijuan Jia, Jessica McLachlan, Jiayan Xu, Seyed M. Tadayyon, S. Holger Eichhorn
Publikováno v:
Canadian Journal of Chemistry. 84:998-1005
Noble metal nanoparticles (NPs) prepared by a surfactant-free single-phase solution method have been proposed to contain fewer ionic contaminants than similar NPs prepared by a two-phase method. Reported herein is the possible contamination of Au and
Publikováno v:
Journal of Molecular Endocrinology. 26:145-154
The effect of treatment with a 0.03% fatty acid (FA) cocktail on leptin-receptor-mediated STAT (signal transducers and activators of transcription) activation in the rat insulinoma cell line BRIN-BD11 was investigated. Leptin (10 nM) stimulated the t
Autor:
F. Mehraein-Ghomi, S. Gnaneshan, Lida Hashemzadeh-Bonehi, L. A. Hunt, Jenny K. Broome-Smith, Emma S. Hennessey, M. Tadayyon
Publikováno v:
Molecular Membrane Biology. 11:3-8
Most proteins destined for secretion are synthesized with amino-terminal extensions, known as signal peptides, which play a vital role in their translocation across the membrane bordering the cytoplasm. Following translocation across the eukaryotic e
Autor:
Nils O. Petersen, Seyed M. Tadayyon, Yi Y. Zuo, Fred Possmayer, Ruud A. W. Veldhuizen, Eleonora Keating
Publikováno v:
Biochimica et biophysica acta. 1818(5)
article i nfo The exact mechanism by which pulmonary surfactant films reach the very low surface tensions required to stabilize the alveoli at end expiration remains uncertain. We utilized the nanoscale sensitivity of atomic force microscopy (AFM) to