Zobrazeno 1 - 6
of 6
pro vyhledávání: '"M T Johnstone"'
Publikováno v:
Circulation. 84:2568-2573
BACKGROUND To examine the effect of plasminogen activator therapy on vascular permeability, we used a modified rabbit mesenteric model of extravascular tissue accumulation of radiolabeled albumin. METHODS AND RESULTS Albumin deposition was measured a
Publikováno v:
Circulation. 102(1)
Publikováno v:
Thrombosis and haemostasis. 71(4)
In a continuing effort to create an agent which has both thrombolytic and antithrombotic properties, streptokinase (SK) was covalently bound to the potent antithrombin agent recombinant hirudin (rHir). Linkage of SK to 125I-rHir was accomplished via
Autor:
Mark A. Creager, Jorge A. Cusco, Shelly J. Creager, M T Johnstone, B K Lee, Kathleen M. Scales
Publikováno v:
Circulation. 88(6)
BACKGROUND Endothelium-dependent vasodilation is abnormal in experimental models of diabetes mellitus. We postulated that abnormalities of endothelial function are also present in patients with insulin-dependent diabetes mellitus and may contribute t
Autor:
LeRoy E. Rabbani, L. Collins, D George, M T Johnstone, R. T. Moore, Joseph Loscalzo, M A Rudd
Publikováno v:
Circulation research. 70(4)
To evaluate the effect of thrombin on the dynamics of thrombolysis, we infused rabbits with heparin or hirudin alone or in conjunction with tissue-type plasminogen activator (t-PA) and monitored the kinetics of fibrinolysis and changes in ex vivo pla
Autor:
Thomas C. Andrews, Milton C. Weinstein, D George, J A Ware, M A Rudd, Joseph Loscalzo, M T Johnstone
Publikováno v:
Circulation. 82(6)
The mechanism by which treatment with thrombolytic agents causes bleeding is not known. Recently, frequency of bleeding events has been shown to correlate with bleeding time, particularly in individuals treated with aspirin. We examined the effects o