Zobrazeno 1 - 10
of 25
pro vyhledávání: '"M T Ergin"'
Autor:
Nitya G. Chakraborty, Li Li, Jonathan R. Sporn, Scott H. Kurtzman, M. T. Ergin, Bijay Mukherji
Publikováno v:
The Journal of Immunology. 162:5576-5583
Because APCs play a crucial role in the generation of T cell-mediated immune responses, numerous clinical trials with APC-based vaccines have been initiated in different types of human cancers. Encouraging results have emerged from some of these init
Autor:
J. L. Meehan, Jonathan R. Sporn, S K Kurtzman, Bijay Mukherji, Nitya G. Chakraborty, Seiji Yamasaki, M. T. Ergin, Harold Yamase, J Ozols, Takashi Okino
Publikováno v:
Proceedings of the National Academy of Sciences. 92:8078-8082
Human melanoma cells can process the MAGE-1 gene product and present the processed nonapeptide EADPTGHSY on their major histocompatibility complex class I molecules, HLA-A1, as a determinant for cytolytic T lymphocytes (CTLs). Considering that autolo
Publikováno v:
Immunology Letters. 35:51-57
Recently, there has been a surge of interest in gene therapy in cancer particularly with cytokine transduced tumor cells as a novel form of tumor vaccine. In two autologous human tumor systems, using the tumor cells engineered to produce interleukin-
Publikováno v:
Clinical Immunology and Immunopathology. 59:407-416
A functional analysis of tumor-infiltrating lymphocytes (TILs) from renal cell carcinoma (RCC) and malignant melanoma was performed. TILs were expanded in recombinant interleukin-2 (50 U/ml) in Iscoves medium. Phenotypic and functional (cytolytic vs
Publikováno v:
The Journal of Immunology. 145:2359-2364
The host immune response toward autologous human cancer is subject to regulation by the immunoregulatory network. We show that certain CD4+ T cell clones, derived from melanoma involved lymph node lymphocytes and from PBL stimulated by autologous mel
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 162(9)
Because APCs play a crucial role in the generation of T cell-mediated immune responses, numerous clinical trials with APC-based vaccines have been initiated in different types of human cancers. Encouraging results have emerged from some of these init
Publikováno v:
Neuroradiology. 40(8)
We report an unusual case of massive intraventricular spread of B-cell lymphoma of the breast, presenting with rapidly progressive ataxia and impaired cognition with need for ventriculostomy. Rapid resolution followed intravenous dexamethasone and ra
Autor:
Jonathan R. Sporn, Scott H. Kurtzman, Anne F. Tortora, Bijay Mukherji, Nitya G. Chakraborty, Harold Yamase, M. T. Ergin
Publikováno v:
Cancer immunology, immunotherapy : CII. 47(1)
The discoveries of human melanoma-associated antigens in molecular terms have renewed interest in peptide- or peptide- and antigen-presenting-cell (APC)-based cancer vaccines. Considering the limited scope of immunization using defined peptides, we h
Publikováno v:
Connecticut medicine. 62(4)
A case of intrinsic hemangioma of the peripheral nerves and the diagnostic and therapeutic problems associated with these tumors is reviewed. Of the preoperative studies available, magnetic resonance imaging and to a lesser degree computed axial tomo
Publikováno v:
Cancer research. 56(11)
Identification of human melanoma-associated peptide antigens for CTLs has opened unprecedented opportunities for active specific immunotherapy for melanoma with synthetic peptide. We have shown that immunization with a MAGE-1 gene encoded nonapeptide