Zobrazeno 1 - 10
of 35
pro vyhledávání: '"M T, Webster"'
Autor:
A. Donovan, Capili Allan, K. J. Turner, Michelle Pirruccello-Straub, K. Long, W. McConaughy, N. K. Mahanthappa, Stefan Wawersik, Gregory J. Carven, L. Salta, C. Boston, M. T. Webster, Justin W. Jackson
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Many growth factors are intimately bound to the extracellular matrix, with regulated processing and release leading to cellular stimulation. Myostatin and GDF11 are closely related members of the TGFβ family whose activation requires two proteolytic
Publikováno v:
Journal of Neural Transmission. 105:839-853
The mismetabolism of amyloid precursor protein (APP), favouring the production of A beta, is considered to be central to the pathogenesis of Alzheimer's disease (AD). However it remains to be established whether the causative factor is the reported t
Autor:
Rudolph E. Tanzi, Paul T. Francis, F E Sherriff, David M. Bowen, Kevin M. Felsenstein, M.-T. Webster, Gopal Thinakaran, Wilma Wasco, Brian Pearce, N Groome
Publikováno v:
Biochemical Journal. 310:95-99
A monoclonal antibody, 3B11, was raised to a novel protein, amyloid precursor-like protein 2, which did not recognize amyloid precursor protein. Multiple bands were detected in human brain fractions and cell lysate by Western blotting, indicating the
Autor:
A. W. Procter, P. T. Francis, C. Holmes, M-T. Webster, M. Qume, G. C. Stratmann, R. Doshi, D. M. A. Mann, P. J. Harrison, R. C. A. Pearson, D. M. Bowen
Publikováno v:
Acta Neuropathologica. 88:545-552
Post-mortem cerebral cortex from 15 demented patients was specially collected to minimise autolysis and two membrane fractions and one soluble fraction were quantitatively examined for the major species of beta-amyloid precursor protein (APP) of high
Autor:
Andrew W. Procter, M.-T. Webster, David M. Bowen, D. M. A. Mann, Rupak Doshi, Paul T. Francis, G. C. Stratmann
Publikováno v:
Brain Research. 644:347-351
Concentrations of amyloid precursor protein (APP)-like immunoreactivity (APPLIR) have been determined by Western blotting in a soluble fraction and two membrane fractions of two areas of brain cortex from patients with Alzheimer's disease (AD) and ot
Autor:
J. Pearson, C.J. Maclean, N.P. Luff, M.-T. Webster, M.J. Halsey, Brian S. Meldrum, E.M. Ward, A. Charlett, P.C. Pearce
Publikováno v:
Neuropharmacology. 30:787-796
Neurophysiological interactions between the competitive N-methyl-D-aspartate (NMDA) preferring receptor antagonist, CPP (3-((+-)-2-carboxypiperazine-4-yl)-propyl-1-phosphonate) and the high pressure neurological syndrome (HPNS) have been investigated
Publikováno v:
Journal of hazardous materials. 69(1)
Conventional soil vapor extraction (SVE) systems have a limited effectiveness at removing semi-volatile chemicals from soil. Raising chemical vapor pressures by heating soil in-situ can decrease remediation time and help remove semi-volatile chemical
Predicting hydrocarbon removal from thermally enhanced soil vapor extraction systems. 2. Field study
Publikováno v:
Journal of hazardous materials. 69(1)
The effectiveness of a thermally enhanced soil vapor extraction (SVE) system to remove semi-volatile organic chemicals (SVOCs) was investigated in a field study. The data allowed the calculations of SVOC removal rates at several temperatures. A previ
Publikováno v:
British journal of haematology. 105(2)
Venous thrombosis is a common problem, predominantly afflicting people of European origin. This European predisposition has been explained to some extent by the recent characterization of factor V Leiden, and the G20210A prothrombin variant. Although
Publikováno v:
Dementia (Basel, Switzerland). 5(2)
Cerebral cortex from humans and rats was extracted sequentially with detergent-containing and low-ionic-strength buffers. The resulting pellet was extracted with detergent/high-ionic-strength buffer to yield a soluble enzyme preparation. This was inc