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pro vyhledávání: '"M T, Tulp"'
Autor:
I, van Wijngaarden, D, Hamminga, R, van Hes, P J, Standaar, J, Tipker, M T, Tulp, F, Mol, B, Olivier, A, de Jonge
Publikováno v:
Journal of medicinal chemistry. 36(23)
On the basis of the structures of ondansetron and GR 65,630, its ring-opened C-linked methylimidazole analogue, novel 1,7-annelated indole derivatives were synthesized as potential 5-HT3 antagonists. Receptor binding studies show that all compounds d
Publikováno v:
Archives internationales de pharmacodynamie et de therapie. 287(2)
Clovoxamine, a nontricyclic antidepressant, has a dual action in blocking the reuptake of both noradrenaline and serotonin. Acute in vitro receptor binding studies showed that clovoxamine has little affinity for muscarinic, histaminergic, serotonergi