Zobrazeno 1 - 7
of 7
pro vyhledávání: '"M T, Rotondo"'
Autor:
Annamaria Pace, Giulia Renda, Carlo Patrono, Paola Patrignani, Giovanna Santini, M. R. Panara, M. T. Rotondo, Maria G. Sciulli, Roberto Padovano
Publikováno v:
Clinical Pharmacology & Therapeutics. 63:672-681
Background The aim of this study was to test the hypothesis that nimesulide, a nonsteroidal antiinflammatory drug, or its principal metabolite 4-hydroxynimesulide, is a selective inhibitor of prostaglandin H synthase-2 in human beings. Methods Hepari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eac123d5683352e6a0b2aac6052b26d6
https://doi.org/10.1016/s0009-9236(98)90091-1
https://doi.org/10.1016/s0009-9236(98)90091-1
Autor:
M R, Panara, G, Renda, M G, Sciulli, G, Santini, M, Di Giamberardino, M T, Rotondo, S, Tacconelli, F, Seta, C, Patrono, P, Patrignani
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 290(1)
We evaluated whether therapeutic blood levels of meloxicam are associated with selective inhibition of monocyte cyclooxygenase (COX)-2 in vitro and ex vivo. Concentration-response curves for the inhibition of monocyte COX-2 and platelet COX-1 were ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c8fa341aa65f10fed60c95e4248a17f6
https://pubmed.ncbi.nlm.nih.gov/10381787
https://pubmed.ncbi.nlm.nih.gov/10381787
Autor:
M. R. Panara, Paola Patrignani, Maria G. Sciulli, Maria di Giamberardino, Roberto Padovano, Piero Del Soldato, Giovanna Santini, M. T. Rotondo
Publikováno v:
European journal of pharmacology. 316(1)
The aim of our study was to evaluate the selectivity of flurbiprofen and flurbinitroxybutylester for inhibition of the cyclooxygenase activity of prostaglandin endoperoxide synthase-2 vs. prostaglandin endoperoxide synthase-1 in human blood monocytes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ab71b41736deed2437f091732c9e007
https://pubmed.ncbi.nlm.nih.gov/8982652
https://pubmed.ncbi.nlm.nih.gov/8982652
Autor:
Maria di Giamberardino, Giovanni Ciabattoni, Jacques Maclouf, M. T. Rotondo, Maria G. Sciulli, Anita Greco, Giovanna Santini, M. R. Panara, Paola Patrignani, Carlo Patrono
1. The isoprostane 8-epi-prostaglandin (PG)F2 alpha is produced by free radical-catalyzed peroxidation of arachidonic acid. It may also be formed as a minor product of the cyclo-oxygenase activity of platelet PGH synthase (PGHS)-1. We investigated 8-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53a266052c8b5da6f742549c2bc50318
https://europepmc.org/articles/PMC1909586/
https://europepmc.org/articles/PMC1909586/
Autor:
M. di Giamberardino, Francesco Cipollone, Giovanna Santini, Roberto Padovano, Maria G. Sciulli, M. T. Rotondo, M. R. Panara, Carlo Patrono, Paola Patrignani
Publikováno v:
Eicosanoids ISBN: 9781489902023
The conversion of arachidonic acid to prostaglandin(PG)H2 is catalyzed by PG-endoperoxide synthase (PGHS) which exhibits both cyclooxygenase and peroxidase activities (DeWitt, 1991). PGH2 is further metabolized by other enzymes to various prostanoids
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b605d31b88f38c49ff5fee16a971836
https://doi.org/10.1007/978-1-4899-0200-9_4
https://doi.org/10.1007/978-1-4899-0200-9_4
Autor:
Roberto Padovano, Francesco Cipollone, M. R. Panara, Giovanna Santini, Maria G. Sciulli, Paola Patrignani, M. di Giamberardino, Carlo Patrono, M. T. Rotondo
Publikováno v:
Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors ISBN: 9789401090315
The conversion of arachidonic acid to prostaglandin (PG) H2 is catalysed by PG-endoperoxide synthase (PGHS) which exhibits both cyclooxygenase (COX) and peroxidase activities1. PGH2 is further metabolized by other enzymes to various prostanoids (PGs,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6dac7f689a66bdb988e735a64189fa6b
https://doi.org/10.1007/978-94-010-9029-2_7
https://doi.org/10.1007/978-94-010-9029-2_7
Autor:
Francesco Cipollone, Paola Patrignani, Maria G. Sciulli, Roberto Padovano, Franco Cuccurullo, Carlo Patrono, Anita Greco, Giovanna Santini, M. T. Rotondo, M. R. Panara, Maria di Giamberardino
Publikováno v:
Scopus-Elsevier
1. We have evaluated the selectivity of ketoprofen and two novel nonsteroidal anti-inflammatory drugs, N-[2-(cyclohexyloxy)-4-nitrophenyl]methanesulphonamide (NS-398) and 5-methanesulphonamido-6-(2,4-difluorothiophenyl)-1-indano ne (L-745,337), in in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37c330f8d858f28c356f2dd818f0f277
https://europepmc.org/articles/PMC1909061/
https://europepmc.org/articles/PMC1909061/