Zobrazeno 1 - 10
of 157
pro vyhledávání: '"M T, Lotze"'
Publikováno v:
HNO. 68:71-79
Exosomes are the current primary research focus of Dr. Theresa L. Whiteside. They are key mediators of intercellular communication in the head and neck, as well as other sites. Their effects in the tumor microenvironment are manifold and include supp
Publikováno v:
Methods in molecular medicine. 7
Considerable evidence has accumulated indicating that cultured human or rodent tumor cells can be successfully transduced with cytokine genes and selected in the appropriate antibiotic-containing culture media. The selected transductants are generall
Autor:
M T Lotze
Publikováno v:
Gene Therapy. 13:191-193
Publikováno v:
Current Problems in Surgery. 33:961-1041
Publikováno v:
The Journal of Immunology. 157:231-238
Cellular IL-10 (cIL-10), the collective term for human and murine IL-10, has both stimulatory and inhibitory effects on diverse cell types, including costimulation of T cell proliferation, chemoattraction of CD8+ T cells, and stimulation of lymphokin
Autor:
H. Rabinowich, L. Zitvogel, K. Halusczcak, W. Walter, R. Duquesnoy, Markus Maeurer, D. Martin, M. T. Lotze, W. Storkus, Kaihong Liu
Publikováno v:
The Journal of Experimental Medicine
gammadelta T cells can be grouped into discrete subsets based upon their expression of T cell receptor (TCR) variable (V) region families, their tissue distribution, and their specificity. Vdelta2+ T cells constitute the majority of gammadelta T cell
Autor:
L Qin, K D Chavin, Y Ding, H Tahara, J P Favaro, J E Woodward, T Suzuki, P D Robbins, M T Lotze, J S Bromberg
Publikováno v:
The Journal of Immunology. 156:2316-2323
A murine heterotopic, nonvascularized cardiac allograft model was used to examine the effects of the immunosuppressive cytokine, viral IL-10 (vIL-10), delivered by gene transfer on graft rejection. Retroviral-mediated gene transfer and expression of
Publikováno v:
The Journal of Immunology. 148:2118-2125
As a multifunctional cytokine that can augment certain T cell responses, IL-4 is being evaluated currently as a possible therapeutic agent in the treatment of cancer patients. In this report, PBMC were isolated from such patients before and after IL-
Publikováno v:
Blood. 79:1491-1495
Human basophils possess receptors for interleukin-2 (IL-2) and IL-4. The effect of 3 days of intravenous administration of IL-2 and/or IL-4 on basophil histamine release was examined in three groups of patients receiving IL-2, IL-4, or the combinatio
Publikováno v:
The Journal of Immunology. 146:150-155
Induction of lymphokine-activated killer (LAK) activity by IL-2 has been described and characterized as broadly cytolytic activity against both fresh and cultured tumors. rIL-7 in the absence of IL-2 also induces LAK activity in human cells. This act