Zobrazeno 1 - 2
of 2
pro vyhledávání: '"M T, Kuhfeld"'
Autor:
A H, Dantzig, R L, Shepard, K L, Law, L, Tabas, S, Pratt, J S, Gillespie, S N, Binkley, M T, Kuhfeld, J J, Starling, S A, Wrighton
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 290(2)
Overexpression of ATP-dependent drug efflux pumps, P-glycoprotein (Pgp) or multidrug resistance-associated protein (MRP), confers multidrug resistance to tumor cells. Modulators of multidrug resistance block the action of these pumps, thereby sensiti
Publikováno v:
Pharmaceutical research. 11(10)
Various processes involved in the transcellular transport (TT) of loracarbef (LOR) were studied in the Caco-2 cell monolayer, a cell culture model of the small intestinal epithelium. The results provide support for presence of two AP to BL peptide TT