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Autor:
D J, Pettibone, B V, Clineschmidt, M T, Kishel, E V, Lis, D R, Reiss, C J, Woyden, B E, Evans, R M, Freidinger, D F, Veber, M J, Cook
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 264(1)
L-366,509, a member of a novel class of nonpeptidyl compounds, has been characterized as an orally active oxytocin (OT) antagonist. L-366,509 exhibits a moderate binding affinity (K(i) values, 370-780 nM) for the rat, rhesus and human uterine OT rece