Zobrazeno 1 - 10
of 86
pro vyhledávání: '"M Szczepańska-Konkel"'
Publikováno v:
British Journal of Pharmacology. 144:1109-1117
1. Diadenosine polyphosphates (P(1),P(3)-diadenosine triphosphate, Ap(3)A; P(1),P(4)-diadenosine tetraphosphate, Ap(4)A; and P(1),P(5)-diadenosine pentaphosphate, Ap(5)A) are vasoactive molecules. The experimental model of isolated rat renal glomerul
Publikováno v:
Acta physiologica (Oxford, England). 202(2)
To investigate in vivo effects of P2X receptor activation on sodium and water excretion in urine.The clearance experiments were carried out in anaesthetized rats during intravenous infusion (2 μmol kg(-1) + 20 nmol (kg min)(-1) , v = 40 μL min(-1))
Publikováno v:
Biochemical and Biophysical Research Communications. 181:871-876
We investigated the role of ANF and potassium channels in dynamics of glomeruli isolated from low and normal-sodium rats. The ANG II - induced decrease glomerular size (36%) and (18%) in low and normal-sodium rats, respectively. ANF or cicletanine sh
Publikováno v:
Biochemical and Biophysical Research Communications. 170:596-602
Atrial natriuretic factor administered in the large dose did not change glomerular filtration rate, but it was diuretic in low-sodium rats. In response to ANF, excretion of c-GMP was decreased in low-sodium rats in comparison with normal-sodium rats.
Publikováno v:
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 59(1)
Previous studies from our laboratory have reported a marked reduction in glomerular filtration rate (GFR) and sodium reabsorption in renal proximal tubule during intravenous infusion of P(1),P(4)-diadenosine tetraphosphate (Ap(4)A) at dose of 1.0 mic
Publikováno v:
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 56(1)
Cyclic AMP has been generally recognised as activator of cAMP-dependent protein kinases. However, there is little evidence about role of cAMP-dependent protein kinase (PKA), in particular izoenzymes PKA-I and PKA-II, in glomeruli contractility. We me
Autor:
M, Szczepańska-Konkel, M, Jankowski, A, Stiepanow-Trzeciak, A, Rudzik, T, Pawełczyk, S, Angielski
Publikováno v:
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 54(1)
Glomerular filtration rate (GFR) in response to adenosine precursor, NAD, and glomeruli contractility in response to adenosine were evaluated in streptozotocin-induced diabetic rats with severe (blood glucose 27.8 +/- 1.2 mmol/L) and moderate hypergl
Autor:
M, Szczepańska-Konkel, G, Langner, G, Bednarczuk, A, Stiepanow-Trzeciak, M, Jankowski, S, Angielski
Publikováno v:
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 54(2)
Effects of Ap4A and NAD--precursor of adenosine, on renal plasma flow (RPF), glomerular filtration rate (GFR) and urine excretion were determined in the anaesthetised rats. Infusion of Ap4A or NAD (i.v., bolus--1 micromol/kg followed by 10 nmol/min/k
Publikováno v:
Medical science monitor : international medical journal of experimental and clinical research. 7(4)
Atrial natriuretic factor (ANF)-induced increase in glomerular filtration rate (GFR) is inhibited on low sodium intake. It has been shown that activation of renin-angiotensin system on low sodium intake antagonizes the biological effect of ANF by int