Zobrazeno 1 - 10
of 14
pro vyhledávání: '"M Susana, Leguizamón"'
Inactive trans-Sialidase Expression in iTS-null Trypanosoma cruzi Generates Virulent Trypomastigotes
Autor:
Carla A. Pascuale, Juan M. Burgos, Miriam Postan, Andrés B. Lantos, Adriano Bertelli, Oscar Campetella, M. Susana Leguizamón
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
Disclosing virulence factors from pathogens is required to better understand the pathogenic mechanisms involved in their interaction with the host. In the case of Trypanosoma cruzi several molecules are associated with virulence. Among them, the tran
Externí odkaz:
https://doaj.org/article/e57613a4a7f3475b9c1eb7758372953c
Autor:
Javier M. Urquiza, Juan M. Burgos, Diego S. Ojeda, Carla A. Pascuale, M. Susana Leguizamón, Jorge F. Quarleri
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
The protozoan Trypanosoma cruzi is the etiological agent of Chagas disease. In immunosuppressed individuals, as it occurs in the coinfection with human immunodeficiency virus (HIV), the central nervous system may be affected. In this regard, reactiva
Externí odkaz:
https://doaj.org/article/25cae8b826d048aeba3fb5e2d5455b35
Autor:
Carla A, Pascuale, Juan M, Burgos, Miriam, Postan, Andrés B, Lantos, Adriano, Bertelli, Oscar, Campetella, M Susana, Leguizamón
Publikováno v:
Frontiers in Cellular and Infection Microbiology
Disclosing virulence factors from pathogens is required to better understand the pathogenic mechanisms involved in their interaction with the host. In the case of Trypanosoma cruzi several molecules are associated with virulence. Among them, the tran
Autor:
Martha V. Cardinal, Paula A. Sartor, Marcela Orozco, Ricardo E. Gürtler, M. Susana Leguizamón
Publikováno v:
Clinical and Vaccine Immunology. 18:984-989
The detection ofTrypanosoma cruziinfection in domestic dogs and cats is relevant to evaluating human transmission risks and the effectiveness of insecticide spraying campaigns. However, the serological assays routinely used are associated with cross-
Autor:
Alejandra Hidalgo, Oscar Campetella, Juan Mucci, Esteban Mocetti, Pablo Argibay, M. Susana Leguizamón
Publikováno v:
Proceedings of the National Academy of Sciences. 99:3896-3901
Trypanosoma cruzi , the causative agent of Chagas' disease, induces transient thymic aplasia early after infection—a phenomenon that stills lacks a molecular explanation. The parasite sheds an enzyme known as trans -sialidase (TS), which is able to
Autor:
Pablo Argibay, M. Susana Leguizamón, Oscar Campetella, Esteban Mocetti, Hernán García Rivello
Publikováno v:
The Journal of Infectious Diseases. 180:1398-1402
Trypanosoma cruzi, the etiologic agent of Chagas' disease, expresses trans-sialidase, an enzyme able to direct transfer of sialyl residues among macromolecules. The enzyme is shed and can be detected in blood during the acute phase of the disease. Se
Autor:
Edward L. Murphy, Cecilia Gamba, Ivana Colaianni, Paula A. Sartor, Mirta C. Remesar, M. Susana Leguizamón, Torsten B. Neilands, Ana del Pozo, María A. Ridolfi, Mónica Puppo, Silvina Kuperman
Publikováno v:
Transfusion. 49(11)
Chagas’ disease or American trypanosomiasis is a chronic disease caused by the parasite Trypanosoma cruzi and represents a significant health problem in Latin American countries. The parasite is transmitted to humans or other mammals by triatomine
Publikováno v:
Cellular microbiology. 8(7)
Summary The trans -sialidase, a modified sialidase that trans- fers sialyl residues among macromolecules, is a unique enzymatic activity expressed by some para- sitic trypanosomes being essential for their survival in the mammalian host and/or in the
Evaluation of Brucella abortus phosphoglucomutase (pgm) mutant as a new live rough-phenotype vaccine
Publikováno v:
Infection and immunity. 71(11)
Brucella abortusS19 is the vaccine most frequently used against bovine brucellosis. Although it induces good protection levels, it cannot be administered to pregnant cattle, revaccination is not advised due to interference in the discrimination betwe
Autor:
M. Susana Leguizamón, Carlos A. Buscaglia, Tamara A. Pitcovsky, Paula Alvarez, Oscar Campetella
Publikováno v:
Infection and immunity. 69(12)
The repetitive shed acute-phase antigen (SAPA) from Trypanosoma cruzi was thoroughly mapped by SPOT peptides and phage display strategies, showing that a single SAPA repeat is composed of multiple overlapping B-cell epitopes. We propose that this int