Druggability and Binding Site Interaction Studies of Potential Metabolites Isolated from Marine Sponge Aurora globostellata against Human Epidermal Growth Factor Receptor-2

Autor: Raj Bhaskaran, Dorairaj Sudarsanam, A. Suresh, M Sugappriya, Jerrine Joseph

Publikováno v: Bioinformation

To study the involvement of compounds stigmasterol and oleic acid isolated from marine sponge Aurora globostellata and docking against the Human Epidermal Growth Factor Receptor-2 in breast cancer. The comparative molecular docking was performed with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c61a6c9db43dd2ca0741c964d56548f4
http://europepmc.org/articles/PMC5609291

Modeling of ATP-Sensitive Inward Rectifier Potassium Channel 11 and Inhibition Mechanism of the Natural Ligand, Ellagic Acid, Using Molecular Docking

Autor: Sangeetha M Priyadarshini, Alex J Mathew, M Sugappriya, N. Nixon Raj

Publikováno v: Advances in Experimental Medicine and Biology ISBN: 9781441959126

Diabetes mellitus is a disorder in which blood sugar (glucose) levels are abnormally high because the body does not produce enough insulin to meet its needs. Post-prandial hyperglycemia (PPHG) is an independent risk factor for the development of macr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7d073c2cab0480328791767b36537bb7
https://doi.org/10.1007/978-1-4419-5913-3_55

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Druggability and Binding Site Interaction Studies of Potential Metabolites Isolated from Marine Sponge Aurora globostellata against Human Epidermal Growth Factor Receptor-2.

Autor: Sugappriya M; Research and development centre, Bharathiar University, Coimbatore 641 046, Tamilnadu, India., Sudarsanam D; Department of Zoology and Advanced Biotechnology, Loyola college, Chennai 600034,Tamil nadu, India., Bhaskaran R; School of Biotechnology and genetic engineering Bharathiar University, Coimbatore 641 046, Tamilnadu, India., Joseph J; Centre for Drug Discovery and Development, Jeppiaar Research park, Sathyabama University, Chennai 600119,Tamilnadu, India., Suresh A; Centre for Drug Discovery and Development, Jeppiaar Research park, Sathyabama University, Chennai 600119,Tamilnadu, India.

Publikováno v: Bioinformation [Bioinformation] 2017 Aug 31; Vol. 13 (8), pp. 261-268. Date of Electronic Publication: 2017 Aug 31 (Print Publication: 2017).