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Akademický článek
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Autor:
Joel M. Schrock, Gavril W. Pasternak, Christina M. Spino, Stacy M. Stabler, Charles G. Longen, Felix J. Kim, Jacqueline C. Marino
Publikováno v:
Molecular pharmacology. 84(5)
The Sigma1 receptor (Sigma1) is an endoplasmic reticulum (ER) integral membrane protein that is highly expressed in a number of cancer cell lines. Small molecule compounds targeting Sigma1 (Sigma1 ligands) inhibit cancer cell proliferation and induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efc5977b166539ad92ce5970f166bc75
https://pubmed.ncbi.nlm.nih.gov/24006496
https://pubmed.ncbi.nlm.nih.gov/24006496
Autor:
Amid Khan, Eric Gnall, MaryAnn C. Wertan, Marwan Badri, Francis P. Sutter, Timothy Shapiro, Paul Coady, Christina M. Spino, Frank C. McGeehin
Publikováno v:
Journal of the American College of Cardiology. 67:112
Multiple options for the treatment of multivessel disease now exist including hybrid revascularization. Nuances in hybrid revascularization need further evaluation including timing of these procedures and optimal antiplatelet therapy. We retrospectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c47c0d4888af4dc26bf3269f2cd940ab
https://doi.org/10.1016/s0735-1097(16)30113-9
https://doi.org/10.1016/s0735-1097(16)30113-9
Publikováno v:
Biochemical and biophysical research communications. 426(2)
Treatment with sigma1 receptor (Sigma1) ligands can inhibit cell proliferation in vitro and tumor growth in vivo. However, the cellular pathways engaged in response to Sigma1 ligand treatment that contribute to these outcomes remain largely undefined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97221e023584c85ef398e5d216aa4500
https://pubmed.ncbi.nlm.nih.gov/22925888
https://pubmed.ncbi.nlm.nih.gov/22925888
Publikováno v:
Medical Hypotheses. 51:489-491
Several clinical studies demonstrate reduced serum concentrations of renally excreted drugs in patients with cystic fibrosis (CF). To explain this phenomenon, we propose a model supporting increased proximal tubular secretion of certain drugs in indi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63a01c1627223164f9dbe4f8fa2a5ee0
https://doi.org/10.1016/s0306-9877(98)90070-6
https://doi.org/10.1016/s0306-9877(98)90070-6
Publikováno v:
Mutagenesis. 18(5)
Measurements of chromosomal aberrations were made in 10 thalassaemia major patients treated long-term with deferiprone (at least 5 years) and compared with an equal number of patients matched for age, sex and iron overload, treated long-term with def
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a95d57d3e9eaf1685beff18052735bb2
https://pubmed.ncbi.nlm.nih.gov/12960415
https://pubmed.ncbi.nlm.nih.gov/12960415
Publikováno v:
Pharmaceutical research. 13(6)
For the assessment of bioequivalence it is assumed that drug clearance in each subject on each of the study days is the same and any observed differences in AUC and/or Cmax between a brand and generic formulation are due to differences in bioavailabi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7bc97cd56b54788a3a6f80271c7f0361
https://pubmed.ncbi.nlm.nih.gov/8792420
https://pubmed.ncbi.nlm.nih.gov/8792420
Publikováno v:
Clinical nephrology. 42(1)
Recent studies in adults have suggested that parenteral 1,25-dihydroxyvitamin D3 (1,25[OH]2D3) may have advantages over oral therapy in the management of renal osteodystrophy. The purpose of this study was to determine whether there were clear differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::14bffd2cb607fb3ad18ec22784695801
https://pubmed.ncbi.nlm.nih.gov/7923966
https://pubmed.ncbi.nlm.nih.gov/7923966
Publikováno v:
Pharmacotherapy. 13(3)
Use of addicting drugs among women during pregnancy exposes newborns to potentially serious disorders. A group of symptoms referred to as neonatal withdrawal syndrome (NWS) may occur in infants born to mothers addicted to certain drugs because, at bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ce14f4d5a12048de5b3a2de99aa01d46
https://pubmed.ncbi.nlm.nih.gov/8321734
https://pubmed.ncbi.nlm.nih.gov/8321734