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Akademický článek
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Autor:
Joel M. Schrock, Gavril W. Pasternak, Christina M. Spino, Stacy M. Stabler, Charles G. Longen, Felix J. Kim, Jacqueline C. Marino
Publikováno v:
Molecular pharmacology. 84(5)
The Sigma1 receptor (Sigma1) is an endoplasmic reticulum (ER) integral membrane protein that is highly expressed in a number of cancer cell lines. Small molecule compounds targeting Sigma1 (Sigma1 ligands) inhibit cancer cell proliferation and induce
Autor:
Amid Khan, Eric Gnall, MaryAnn C. Wertan, Marwan Badri, Francis P. Sutter, Timothy Shapiro, Paul Coady, Christina M. Spino, Frank C. McGeehin
Publikováno v:
Journal of the American College of Cardiology. 67:112
Multiple options for the treatment of multivessel disease now exist including hybrid revascularization. Nuances in hybrid revascularization need further evaluation including timing of these procedures and optimal antiplatelet therapy. We retrospectiv
Publikováno v:
Biochemical and biophysical research communications. 426(2)
Treatment with sigma1 receptor (Sigma1) ligands can inhibit cell proliferation in vitro and tumor growth in vivo. However, the cellular pathways engaged in response to Sigma1 ligand treatment that contribute to these outcomes remain largely undefined
Autor:
Hemami, Reyhaneh Mokhtari1, Farhangi, Mahdieh Abbasalizad2 abbasalizad_m@yahoo.com, Rouzi, Mohammad Dehghan3, Abdi, Fatemeh2
Publikováno v:
BMC Endocrine Disorders. 8/5/2024, Vol. 24 Issue 1, p1-16. 16p.
Autor:
Lv, Qingbo1 (AUTHOR), Lin, Jun1,2 (AUTHOR), Huang, He1 (AUTHOR), Ma, Boxuan1 (AUTHOR), Li, Wujiao1 (AUTHOR), Chen, Jiawen1 (AUTHOR), Wang, Meihui1 (AUTHOR), Wang, Xiaoyu3 (AUTHOR) xy_wang@zju.edu.cn, Fu, Guosheng1 (AUTHOR) fugs@zju.edu.cn, Xiao, Yun1 (AUTHOR) xiaoyun@zju.edu.cn
Publikováno v:
Advanced Science. 7/3/2024, Vol. 11 Issue 25, p1-14. 14p.
Publikováno v:
Medical Hypotheses. 51:489-491
Several clinical studies demonstrate reduced serum concentrations of renally excreted drugs in patients with cystic fibrosis (CF). To explain this phenomenon, we propose a model supporting increased proximal tubular secretion of certain drugs in indi
Publikováno v:
Mutagenesis. 18(5)
Measurements of chromosomal aberrations were made in 10 thalassaemia major patients treated long-term with deferiprone (at least 5 years) and compared with an equal number of patients matched for age, sex and iron overload, treated long-term with def
Publikováno v:
Pharmaceutical Research; Feb2006, Vol. 23 Issue 2, p280-290, 11p