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pro vyhledávání: '"M Spella"'
Akademický článek
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Autor:
Maria-Eleni Vazakidou, Androniki Kollintza, Sophia Magkouta, Ioannis Kalomenidis, Ioannis Skianis, M Spella, Georgios T. Stathopoulos, Charalampos Moschos, Apostolos Pappas
Publikováno v:
Cytokine. 118:99-106
Background and objective Anti-angiogenic treatment has been recently shown to be clinically beneficial for mesothelioma patients. Angiopoietins-1 and -2 are key regulators of tumor angiogenesis. Ang-1 is mainly known to promote angiogenesis and vesse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9804fe09b2ce5d7502ef906677930305
https://doi.org/10.1016/j.cyto.2018.08.006
https://doi.org/10.1016/j.cyto.2018.08.006
Autor:
Evanthia Tourkochristou, Marianthi Iliopoulou, Nikolitsa Spiropoulou, Torsten Goldmann, Ioanna Giopanou, Theo Mantamadiotis, Ioannis Lilis, M Spella, Aigli Korfiati, Georgia A. Giotopoulou, Antonia Marazioti, Sebastian Marwitz, Rosero C, Giannoula Ntaliarda, F Kalogianni, Georgios T. Stathopoulos
cAMP response element-binding protein (CREB) mediates proliferative and inflammatory gene transcription in neurodegeneration and cancer, but its role in malignant immune-evasion of lung adenocarcinoma (LUAD) is unknown. We show that human LUAD of smo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02c9ab2ab90af4f78b16a1e5d2308d28
https://doi.org/10.1101/2021.06.19.449094
https://doi.org/10.1101/2021.06.19.449094
Autor:
Fiona E. Yull, G Skiadas, David Brunn, Michael Lindner, M Spella, Giannoula Ntaliarda, Rajkumar Savai, Weiss Sa, Mario A.A. Pepe, Rudolf Hatz, Georgios T. Stathopoulos, Ioanna Giopanou, Petrera A, Ina Koch, Bouloukou E, Timothy S. Blackwell, Antonia Marazioti, Malamati Vreka, Georgia A. Giotopoulou, Ioannis Lilis, Dieter E. Jenne, K. Arendt, Juergen Behr, Stefanie M. Hauck, Anne-Sophie Lamort
The mechanisms tumor cells use to hijack the immune system are largely uncharted. Here we used bioluminescent nuclear factor (NF)-κB reporter mice and macrophages to discover that metastatic tumors trigger NF-κB activation in host macrophages, depe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87f26a1144a8a374660c3b9730c33081
https://doi.org/10.1101/2021.05.20.444963
https://doi.org/10.1101/2021.05.20.444963
Publikováno v:
11.01 - Lung cancer.
Background: Respiratory epithelial dynamics and molecular signatures participating in adult lung maintenance and chemical carcinogenesis need to be clearly identified. Aims: We used mouse models of lung epithelial fate to chart the contribution of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa62f18785c82fd6ca943b993fac49e0
https://doi.org/10.1183/23120541.lsc-2021.78
https://doi.org/10.1183/23120541.lsc-2021.78
Publikováno v:
11.01 - Lung cancer.
Lung cancer is the most lethal cancer worldwide, and its epidemic appears to be on a continuous rise despite smoking prevention and cessation programs. It is generally believed that inflammation alters the microenvironment of tobacco carcinogen-mutat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c998d6a41702e07e5ee23768ce8c62b
https://doi.org/10.1183/23120541.lsc-2021.18
https://doi.org/10.1183/23120541.lsc-2021.18
Publikováno v:
11.01 - Lung cancer.
Malignant pleural effusion (MPE) constitutes a negative prognostic factor in patients suffering from lung adenocarcinoma and mesothelioma. Our lab has previously highlighted a role for NF-κΒ activation in promoting tumor growth and MPE development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff9953ca9056561c6f356a01899f8c34
https://doi.org/10.1183/23120541.lsc-2021.11
https://doi.org/10.1183/23120541.lsc-2021.11
Autor:
Michael Lindner, Marianthi Iliopoulou, Mario A.A. Pepe, Ina Koch, Sophia G. Antimisiaris, Marc Grégoire, I Psallidas, Rudolf Hatz, Ioannis Lilis, Anthi C. Krontira, M Spella, Darcy E. Wagner, Georgios T. Stathopoulos, C. M. Hackl, A. Marazioti, Ioanna Giopanou, Helen Papadaki, S. Deshayes, Malamati Vreka, Christophe Blanquart, Juergen Behr, Anne-Sophie Lamort
Malignant pleural mesothelioma (MPM) arises from mesothelial cells lining the pleural cavity of asbestos-exposed individuals and rapidly leads to the development of pleural effusion and death. MPM harbours loss-of-function mutations in genes likeBAP1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::474f28a1fa8aea25ba88ee8975f0562f
https://doi.org/10.1101/2020.10.22.350850
https://doi.org/10.1101/2020.10.22.350850
Publikováno v:
11.01 - Lung cancer.
The Gauting lung adenocarcinoma donors cohort already established that the age and lung functions influence patients´ survival (1). Here, we conducted a retrospective, exploratory combination of clinical information with tumor tissue profiles in 200
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9362854cb16d8a5da6e77dba07c80c4a
https://doi.org/10.1183/23120541.lsc-2020.54
https://doi.org/10.1183/23120541.lsc-2020.54
Autor:
M Spella, Nikolaos I. Kanellakis, Ian D. Pavord, Georgios T. Stathopoulos, Ioannis Psallidas, Dimitra E. Zazara, Malamati Vreka, Ioanna Giopanou, Antonia Marazioti, Theodora Agalioti, Anastassios D. Giannou, NM Rahman, Ioannis Lilis, Mario A.A. Pepe
Background Carcinogen-inflicted human cancers, including lung tumours harbour thousands of mutations per genome, most of which are unknown (Garraway, LA et al, Cell 2013;153:17–37). Aim To develop a faithful mouse model of human tobacco carcinogen-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe76b3758670d5d9025e4ca2689a8a69
https://ora.ox.ac.uk/objects/uuid:d030287e-8e7a-45fa-97bc-ca604e3689da
https://ora.ox.ac.uk/objects/uuid:d030287e-8e7a-45fa-97bc-ca604e3689da