Zobrazeno 1 - 10
of 58
pro vyhledávání: '"M Sorci-Thomas"'
Publikováno v:
Journal of Lipid Research, Vol 37, Iss 3, Pp 551-561 (1996)
The glycosylation state of lecithin:cholesterol acyltransferase (LCAT) may be important in determining its enzymatic activity. We compared glycosylation structure, enzyme kinetics, and phosphatidylcholine (PC) acyl specificity of human LCAT from four
Externí odkaz:
https://doaj.org/article/0c39bda8b75846889a72388fe42b0075
Publikováno v:
Journal of Lipid Research, Vol 33, Iss 8, Pp 1147-1156 (1992)
In the present study, the accumulation of apolipoproteins (apo) A-I, B, and E in culture medium was measured after 0, 3, 6, 12, and 24 h of incubation with 150 microM docosahexaenoic acid complexed to 75 microM bovine serum albumin (BSA-22:6), either
Externí odkaz:
https://doaj.org/article/b273d71d18c84e9fa9a3ea3fbb7cbac3
Publikováno v:
Journal of Lipid Research, Vol 30, Iss 9, Pp 1397-1403 (1989)
Isocaloric substitution of polyunsaturated fat for saturated fat reduces concentrations of total plasma cholesterol and high density lipoproteins (HDL) in nonhuman primates. The biochemical mechanisms through which polyunsaturated fat lowers plasma H
Externí odkaz:
https://doaj.org/article/eff4eef32c7545d5a4f9888b0a6ad0fc
Publikováno v:
Lymphokine and cytokine research. 13(6)
Monokines, including tumor necrosis factor alpha (TNF-alpha), have been implicated in the pathogenesis of several pathologic processes, including atherosclerosis. Because estrogen has been found to offer a certain degree of protection against atheros
Publikováno v:
The Journal of biological chemistry. 268(28)
A series of mutant apolipoprotein (apoA-I) constructs were designed and then expressed in cell culture to identify structural domains within the mature native apoA-I protein that participate in the activation of the plasma enzyme, lecithin-cholestero
Autor:
M, Sorci-Thomas, M W, Kearns
Publikováno v:
The Journal of biological chemistry. 266(27)
Previous studies have shown that the abundance of apoA-I mRNA in liver and intestine correlates with a 2-3-fold species-specific difference in the plasma concentration of high density lipoprotein and apoA-I. In order to determine the role of gene tra
Publikováno v:
The Journal of biological chemistry. 265(5)
Lecithin-cholesterol acyltransferase (LCAT) catalyzes the intravascular synthesis of lipoprotein cholesteryl esters by converting cholesterol and lecithin to cholesteryl ester and lysolecithin. LCAT is unique in that it catalyzes sequential reactions
Akademický článek
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Publikováno v:
The Journal of biological chemistry. 264(15)
African green monkeys were fed diets containing low and moderate cholesterol concentrations with either polyunsaturated or unsaturated fat as 40% of calories. Plasma total cholesterol, low density lipoprotein (LDL) cholesterol, and apoB concentration
Publikováno v:
The Journal of biological chemistry. 263(11)
Earlier studies have shown that African green monkeys develop a more modest hypercholesterolemia, higher high density lipoprotein (HDL) concentrations, and less atherosclerosis than cynomolgus monkeys fed diets with the same cholesterol content. In t