Zobrazeno 1 - 10
of 1 035
pro vyhledávání: '"M Sherwood"'
Autor:
Nathan P. Ward, Sang Jun Yoon, Tyce Flynn, Amanda M. Sherwood, Maddison A. Olley, Juliana Madej, Gina M. DeNicola
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Cysteine metabolism occurs across cellular compartments to support diverse biological functions and prevent the induction of ferroptosis. Though the disruption of cytosolic cysteine metabolism is implicated in this form of cell death, it is
Externí odkaz:
https://doaj.org/article/3f823335e6504dec9918dcb917a1e452
Autor:
Jason Wallach, Andrew B. Cao, Maggie M. Calkins, Andrew J. Heim, Janelle K. Lanham, Emma M. Bonniwell, Joseph J. Hennessey, Hailey A. Bock, Emilie I. Anderson, Alexander M. Sherwood, Hamilton Morris, Robbin de Klein, Adam K. Klein, Bruna Cuccurazzu, James Gamrat, Tilka Fannana, Randy Zauhar, Adam L. Halberstadt, John D. McCorvy
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Serotonergic psychedelics possess considerable therapeutic potential. Although 5-HT2A receptor activation mediates psychedelic effects, prototypical psychedelics activate both 5-HT2A-Gq/11 and β-arrestin2 transducers, making their respectiv
Externí odkaz:
https://doaj.org/article/30bf5d9d5f33452682a561177a856eb2
Autor:
GA Day, IB McPhee, J Tuffley, F Tomlinson, R Chaseling, S Kellie, I Torode, M Sherwood, K Cutbush, AJ Geddes, B Brankoff
Publikováno v:
Journal of Orthopaedic Surgery, Vol 15 (2007)
Purpose. To determine whether treatment of pineal lesions in children is associated with development of idiopathic scoliosis. Methods. 38 boys and 10 girls with pineal lesions were identified. Their mean age at presentation was 10 years. The pineal p
Externí odkaz:
https://doaj.org/article/56e07ef65f5744098f90ec16d3e7fc00
Autor:
Paul S. Cassidy, Ruth A. Kelly, Ester Reina-Torres, Joseph M. Sherwood, Marian M. Humphries, Anna-Sophia Kiang, G. Jane Farrar, Colm O’Brien, Matthew Campbell, W. Daniel Stamer, Darryl R. Overby, Pete Humphries, Jeffrey O’Callaghan
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 20, Iss , Pp 86-94 (2021)
Systemic or localized application of glucocorticoids (GCs) can lead to iatrogenic ocular hypertension, which is a leading cause of secondary open-angle glaucoma and visual impairment. Previous work has shown that dexamethasone increases zonula occlud
Externí odkaz:
https://doaj.org/article/d2e3a1e4567a46bd80bb688a8be4ad9b
Autor:
Steven W Cotten, Frederick G Strathmann, Frederick S Barrett, Laura Labay, James Mullally, Alexander M Sherwood, Frank Wiegand
Publikováno v:
Clinical Chemistry. 69:319-326
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5013d578c65d39d422c19fb3918a9888
https://doi.org/10.1093/clinchem/hvad016
https://doi.org/10.1093/clinchem/hvad016
Autor:
Elizabeth M. Boazak, Rebecca King, Jiaxing Wang, Cassandra M. Chu, Aaron M. Toporek, Joseph M. Sherwood, Darryl R. Overby, Eldon E. Geisert, C. Ross Ethier
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
The biomechanical properties of the cornea and sclera are important in the onset and progression of multiple ocular pathologies and vary substantially between individuals, yet the source of this variation remains unknown. Here we identify genes putat
Externí odkaz:
https://doaj.org/article/bb3af9c3e014470e9df9a0ee7ec893e7
Autor:
Wei Zhu, Fei Hou, Jingwang Fang, Mohammad Reza Bahrani Fard, Yani Liu, Shouyan Ren, Shen Wu, Yunkun Qi, Shangru Sui, A. Thomas Read, Joseph M. Sherwood, Wei Zou, Hongxia Yu, Jingxue Zhang, Darryl R. Overby, Ningli Wang, C. Ross Ethier, KeWei Wang
Publikováno v:
iScience, Vol 24, Iss 2, Pp 102042- (2021)
Summary: Controlling intraocular pressure (IOP) remains the mainstay of glaucoma therapy. The trabecular meshwork (TM), the key tissue responsible for aqueous humor (AH) outflow and IOP maintenance, is very sensitive to mechanical forces. However, it
Externí odkaz:
https://doaj.org/article/c3fe1e00e07f42fbb931ae6b20207de7
Autor:
Sarah J. Jefferson, Ian Gregg, Mark Dibbs, Clara Liao, Hao Wu, Pasha A. Davoudian, Samuel C. Woodburn, Patrick H. Wehrle, Jeffrey S. Sprouse, Alexander M. Sherwood, Alfred P. Kaye, Christopher Pittenger, Alex C. Kwan
Publikováno v:
Neuropsychopharmacology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e463ccff55f744ab6c81b1a1982ef68e
https://doi.org/10.1038/s41386-023-01572-w
https://doi.org/10.1038/s41386-023-01572-w
Akademický článek
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Publikováno v:
Acta Crystallographica Section E Crystallographic Communications. 78:550-553
The title compound, baeocystin or 4-phosphoryloxy-N-methyltryptamine {systematic name: 3-[2-(methylazaniumyl)ethyl]-1H-indol-4-yl hydrogen phosphate}, C11H15N2O4P, has a single zwitterionic molecule in the asymmetric unit. The molecule has an intramo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0e403b862cd2ea4189e1db0ac43a20c
https://doi.org/10.1107/s2056989022004467
https://doi.org/10.1107/s2056989022004467