Zobrazeno 1 - 10
of 244
pro vyhledávání: '"M Scheithauer"'
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Post-COVID syndrome (PCS) patients have reported a wide range of symptoms, including fatigue, shortness of breath, and diarrhea. Particularly, the presence of gastrointestinal symptoms has led to the hypothesis that the gut microbiome is involved in
Externí odkaz:
https://doaj.org/article/72583739b4ee4a3cad27dd42c2f94ab3
Autor:
Torsten P. M. Scheithauer, Koen Wortelboer, Maaike Winkelmeijer, Xanthe Verdoes, Ömrüm Aydin, Yair I. Z. Acherman, Maurits L. de Brauw, Max Nieuwdorp, Elena Rampanelli, Patrick A. de Jonge, Hilde Herrema
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Individuals with type 2 diabetes (T2D) show signs of low-grade inflammation, which is related to the development of insulin resistance and beta-cell dysfunction. However, the underlying triggers remain unknown. The gut microbiota is a plausible sourc
Externí odkaz:
https://doaj.org/article/bc67ff985f5b49eca2d534bb98fd13f8
Autor:
Koen Wortelboer, Patrick A. de Jonge, Torsten P. M. Scheithauer, Ilias Attaye, E. Marleen Kemper, Max Nieuwdorp, Hilde Herrema
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Bacteriophages (phages) are bacterial viruses that have been shown to shape microbial communities. Previous studies have shown that faecal virome transplantation can decrease weight gain and normalize blood glucose tolerance in diet-induced
Externí odkaz:
https://doaj.org/article/eac20ea80d67444387413ac9fb2a1d78
Autor:
Daniela Stols-Gonçalves, Anne Linde Mak, Mette S. Madsen, Eduard W. J. van der Vossen, Eveline Bruinstroop, Peter Henneman, Femke Mol, Torsten P. M. Scheithauer, Loek Smits, Julia Witjes, Abraham Stijn Meijnikman, Joanne Verheij, Max Nieuwdorp, Adriaan G. Holleboom, Evgeni Levin
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTIndividuals with nonalcoholic fatty liver disease (NAFLD) have an altered gut microbiota composition. Moreover, hepatic DNA methylation may be altered in the state of NAFLD. Using a fecal microbiota transplantation (FMT) intervention, we aime
Externí odkaz:
https://doaj.org/article/614e1712deb34c56a7a373a90e4405b5
Gut virome profiling identifies a widespread bacteriophage family associated with metabolic syndrome
Autor:
Patrick A. de Jonge, Koen Wortelboer, Torsten P. M. Scheithauer, Bert-Jan H. van den Born, Aeilko H. Zwinderman, Franklin L. Nobrega, Bas E. Dutilh, Max Nieuwdorp, Hilde Herrema
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Here, the authors characterize gut viromes in a cohort of individuals with metabolic syndrome, which they find associated with a highly widespread family of gut bacteriophages they name Candidatus Heliusviridae.
Externí odkaz:
https://doaj.org/article/f7a2e23a6c514561aedd199cce580b73
Autor:
Annefleur M. Koopen, Eduardo L. Almeida, Ilias Attaye, Julia J. Witjes, Elena Rampanelli, Soumia Majait, Marleen Kemper, Johannes H. M. Levels, Alinda W. M. Schimmel, Hilde Herrema, Torsten P. M. Scheithauer, Werner Frei, Lars Dragsted, Bolette Hartmann, Jens J. Holst, Paul W. O’Toole, Albert K. Groen, Max Nieuwdorp
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
BackgroundRecent studies demonstrate that a Mediterranean diet has beneficial metabolic effects in metabolic syndrome subjects. Since we have shown that fecal microbiota transplantation (FMT) from lean donors exerts beneficial effects on insulin sens
Externí odkaz:
https://doaj.org/article/4d386c75c38046d78dd5053c4bc2a8f9
Autor:
Torsten P. M. Scheithauer, Guido J. Bakker, Maaike Winkelmeijer, Mark Davids, Max Nieuwdorp, Daniël H. van Raalte, Hilde Herrema
Publikováno v:
Gut Microbes, Vol 13, Iss 1 (2021)
Intestinal immunoglobulins (Ig) are abundantly secreted antibodies that bind bacteria and bacterial components in the gut. This binding is considered to accelerate bacterial transit time and prevent the interaction of potentially immunogenic compound
Externí odkaz:
https://doaj.org/article/5b18bad07ef5401aa7fb0d9286c40ba3
Autor:
Torsten P. M. Scheithauer, Elena Rampanelli, Max Nieuwdorp, Bruce A. Vallance, C. Bruce Verchere, Daniël H. van Raalte, Hilde Herrema
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The gut microbiota has been linked to the development of obesity and type 2 diabetes (T2D). The underlying mechanisms as to how intestinal microbiota may contribute to T2D are only partly understood. It becomes progressively clear that T2D is charact
Externí odkaz:
https://doaj.org/article/de7f960c0ed34613b2f7266fe07fc2d9
Publikováno v:
HNO. 70:751-755
Autor:
Jayron J. Habibe, Maria P. Clemente-Olivo, Torsten P. M. Scheithauer, Elena Rampanelli, Hilde Herrema, Mariska Vos, Arnout Mieremet, Max Nieuwdorp, Daniel H. van Raalte, Etto C. Eringa, Carlie J. M. de Vries
Publikováno v:
Diabetologia, 65(10):s00125-022-05750-1, 1721-1733. Springer, Cham
Diabetologia, 65(10), 1721-1733. Springer Verlag
Habibe, J J, Clemente-Olivo, M P, Scheithauer, T P M, Rampanelli, E, Herrema, H, Vos, M, Mieremet, A, Nieuwdorp, M, van Raalte, D H, Eringa, E C & de Vries, C J M 2022, ' Glucose-mediated insulin secretion is improved in FHL2-deficient mice and elevated FHL2 expression in humans is associated with type 2 diabetes ', Diabetologia, vol. 65, no. 10, pp. 1721-1733 . https://doi.org/10.1007/s00125-022-05750-1
Diabetologia, 65(10), 1721-1733. Springer Verlag
Habibe, J J, Clemente-Olivo, M P, Scheithauer, T P M, Rampanelli, E, Herrema, H, Vos, M, Mieremet, A, Nieuwdorp, M, van Raalte, D H, Eringa, E C & de Vries, C J M 2022, ' Glucose-mediated insulin secretion is improved in FHL2-deficient mice and elevated FHL2 expression in humans is associated with type 2 diabetes ', Diabetologia, vol. 65, no. 10, pp. 1721-1733 . https://doi.org/10.1007/s00125-022-05750-1
Aims/hypothesis The general population is ageing, involving an enhanced incidence of chronic diseases such as type 2 diabetes. With ageing, DNA methylation of FHL2 increases, as well as expression of the four and a half LIM domains 2 (FHL2) protein i