Zobrazeno 1 - 10
of 51
pro vyhledávání: '"M Saugspier"'
Autor:
Anja-Katrin Bosserhoff, Stephanie Arndt, Eva Wacker, Wolfgang E. Thasler, Andreas Koch, M Saugspier, Christoph Dorn, Claus Hellerbrand, Arndt Hartmann
Publikováno v:
Gut. 64:973-981
Objective Bone morphogenetic protein 6 (BMP6) has been identified as crucial regulator of iron homeostasis. However, its further role in liver pathology including non-alcoholic fatty liver disease (NAFLD) and its advanced form non-alcoholic steatohep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03462f01e85bfa51503f656d3d993b3e
https://doi.org/10.1136/gutjnl-2014-306968
https://doi.org/10.1136/gutjnl-2014-306968
Autor:
Arndt Hartmann, Julia C. Engelmann, Anja K. Bosserhoff, M Saugspier, Andreas Koch, Rainer Spang, Christoph Dorn, Claus Hellerbrand, Martina Müller
Publikováno v:
Laboratory Investigation. 94:394-408
Overnutrition is the major cause of nonalcoholic fatty liver disease (NAFLD) and its advanced form nonalcoholic steatohepatitis (NASH). We aimed to develop and characterize a murine model, which resembles both the pathology and nutritional situation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52a5d46f0c95e526be18f0e48d0719c3
https://doi.org/10.1038/labinvest.2014.3
https://doi.org/10.1038/labinvest.2014.3
Autor:
Anja Luehrmann, Reinhard M. K. Thasler, Anja K. Bosserhoff, Seren Lee, M Saugspier, A Mahli, Martina Müller, Claus Hellerbrand, Andreas Koch, Peter Dietrich, Jan Schulze-Luehrmann, J Sommer, Wolfgang E. Thasler
Publikováno v:
Gut. 67(4)
Objective Preoperative chemotherapy with irinotecan is associated with the development of steatohepatitis, which increases the risk of perioperative morbidity and mortality for liver surgery. The molecular mechanisms of this chemotherapeutic complica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26cb731c14b823ce862c79fee2f20faf
https://pubmed.ncbi.nlm.nih.gov/28053052
https://pubmed.ncbi.nlm.nih.gov/28053052
Publikováno v:
Oncology Reports. 28:1423-1428
Bitter acids (BAs) from the hop plant Humulus lupulus L. exhibit multiple beneficial biological properties with promising effects in cancer therapy and prevention, but information regarding the effects on hepatocellular carcinoma (HCC) is missing. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5e05df8efb8418293808d2e89928a9e
https://doi.org/10.3892/or.2012.1925
https://doi.org/10.3892/or.2012.1925
Autor:
Manfred Gehrig, Wolfgang E. Thasler, M Saugspier, Christoph Dorn, Claus Hellerbrand, Jörg Heilmann
Publikováno v:
Experimental and Molecular Pathology. 92:222-228
Female inflorescences of the hop plant Humulus lupulus L. contain a variety of secondary metabolites with bitter acids (BA) as quantitatively dominating secondary metabolites. The use of hops in beer brewing has a long history due to the antibacteria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52d863cfaad189850d3d48b21fb36a28
https://doi.org/10.1016/j.yexmp.2011.11.005
https://doi.org/10.1016/j.yexmp.2011.11.005
Autor:
Matthias S. Klein, Wolfram Gronwald, Christoph Dorn, Claus Hellerbrand, M Saugspier, Peter J. Oefner
Publikováno v:
Metabolomics. 7:237-246
Nonalcoholic fatty liver disease (NAFLD) is a common cause of hepatic dysfunction. The disease spectrum ranges from hepatic steatosis to nonalcoholic steatohepatitis (NASH). The aim of this study was to identify metabolic differences in murine models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ac687545cb69f0c846b1a1ab69b166b
https://doi.org/10.1007/s11306-010-0243-6
https://doi.org/10.1007/s11306-010-0243-6
Publikováno v:
Zeitschrift für Gastroenterologie. 53
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8dc2e309e9340f72f51a706cfdd99d52
https://doi.org/10.1055/s-0035-1568069
https://doi.org/10.1055/s-0035-1568069
Publikováno v:
Zeitschrift für Gastroenterologie. 53
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fed1bacbd3023c7d330e418116818741
https://doi.org/10.1055/s-0034-1397134
https://doi.org/10.1055/s-0034-1397134
Publikováno v:
Zeitschrift für Gastroenterologie. 53
Normal liver reveals only low expression of the facilitative glucose transporter (GLUT) 1. Recently, we have shown that GLUT1 expression is increased in hepatocellular carcinoma (HCC), where GLUT1 acts as a tumor promotor. Hyperglycemia is one of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fea1b9f965c2bf0bc7445f0cced837cd
https://doi.org/10.1055/s-0034-1397068
https://doi.org/10.1055/s-0034-1397068
Autor:
Arndt Hartmann, Christoph Dorn, M Saugspier, Claus Hellerbrand, Anja K. Bosserhoff, Rainer Spang, Martina Müller, Julia C. Engelmann
Publikováno v:
Zeitschrift für Gastroenterologie. 51
The lack of animal models which closely mimic the human situation is one main reason why the molecular mechanisms causing progression from nonalcoholic fatty liver to (NASH) still are elusive. In addition to the quantity of consumed calories, certain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fccc722430b9182d17d939a85e67cf0
https://doi.org/10.1055/s-0032-1331914
https://doi.org/10.1055/s-0032-1331914