Zobrazeno 1 - 10
of 159
pro vyhledávání: '"M Salvino"'
Autor:
EQ Crusoe, J Santos, J Leal, H Santos, A Almeida, L Lucas, M Chaves, V Hungria, M Salvino, MG Arruda
Publikováno v:
Hematology, Transfusion and Cell Therapy, Vol 43, Iss , Pp S194-S195 (2021)
Background: Newly drugs access for MM treatment still a challenge in some countries. One of the most availableinductions for TE NDMM patients (pts) worldwide is cyclophosphamide (C), thalidomide (T) and dexamethasone (d)-(CTd). Dara the first anti- C
Externí odkaz:
https://doaj.org/article/1ce53fea041e4e57be0afd82bb4483ec
Autor:
EQ Crusoe, A Moura, M Chaves, M Salvino, J Santos, H Santos, A Santos, L Lucas, J Leal, MG Arruda
Publikováno v:
Hematology, Transfusion and Cell Therapy, Vol 43, Iss , Pp S261-S262 (2021)
Background: The combination of an anti-CD38 monoclonal antibody, Dara, to the main induction protocols (VRd, VTd,VCd) significantly improved the response rate of TE NDMM before transplantation. However, there is a concern regardingthe possible interf
Externí odkaz:
https://doaj.org/article/dc70877470794cb1a341b115d0d7b621
Autor:
A Santos, H Santos, J Santos, L Lucas, M Salvino, A Almeida, M Santos, A Torres, MG Arruda, EQ Crusoe
Publikováno v:
Hematology, Transfusion and Cell Therapy, Vol 43, Iss , Pp S440- (2021)
Background: The CTD combination have both an immunomodulatory and immunosuppressive activity on multiplemyeloma (MM) patients (pts) treatment. The advance of immunotherapy has been demonstrated by the development ofnew agents like anti CD38-antibody
Externí odkaz:
https://doaj.org/article/4e5c088bc9124f66a4322a1954e36800
Autor:
Cyril T. Namba-Nzanguim, Conrad V. Simoben, Boris D. Bekono, Ian Tietjen, Joel Cassel, Joseph M. Salvino, Luis J. Montaner, Rohan A. Davis, Fidele Ntie-Kang
Publikováno v:
The Microbe, Vol 3, Iss , Pp 100059- (2024)
In silico binding studies were conducted on the known plant-derived polyphenolic tetrameric stilbenoids, (–)-hopeaphenol (1), vaticanol B (2) and vatalbinoside A (3) and their monomeric derivative resveratrol (8), identified from several plant spec
Externí odkaz:
https://doaj.org/article/afc2075cc7264f5a8d0c9e22bd2b420d
Publikováno v:
Molecules, Vol 29, Iss 10, p 2353 (2024)
Quinazolines are an important class of heterocyclic compounds that have proven their significance, especially in the field of organic synthesis and medicinal chemistry because of their wide range of biological and pharmacological properties. Thus, nu
Externí odkaz:
https://doaj.org/article/fe0e1c141f034dbd9e2c88b75375896d
Autor:
Moonsup Jeong, Sagar B. Kudchodkar, Areum Gil, Bohyun Jeon, Gee Ho Park, Youngran Cho, Hyojin Lee, Mi Sun Cheong, Wonil Kim, Yun-Ho Hwang, Jung-Ah Lee, Heeji Lim, Mi Young Kim, Emran O. Lallow, Tej Brahmbhatt, Stephen A. Kania, Nandita C. Jhumur, Jerry W. Shan, Jeffrey D. Zahn, David I. Shreiber, Jonathan P. Singer, Hao Lin, Erin K. Spiegel, Laurent Pessaint, Maciel Porto, Alex Van Ry, Danielle Nase, Swagata Kar, Hanne Andersen, Ian Tietjen, Joel Cassel, Joseph M. Salvino, Luis J. Montaner, Young K. Park, Kar Muthumani, Christine C. Roberts, Joel N. Maslow
Publikováno v:
Frontiers in Virology, Vol 2 (2022)
SARS-CoV-2 is the third pathogenic coronavirus to emerge since 2000. Experience from prior outbreaks of SARS-CoV and MERS-CoV has demonstrated the importance of both humoral and cellular immunity to clinical outcome, precepts that have been recapitul
Externí odkaz:
https://doaj.org/article/c73deb36ca654fa2815416d4cd1e4dd1
Synthesis of both enantiomers and the 13C derivative of CPI-2850, the major metabolite of Devimistat
Publikováno v:
Results in Chemistry, Vol 4, Iss , Pp 100268- (2022)
A practical synthesis of CPI-2850, the major metabolite of Devimistat (CPI-613® (6,8-bis-benzylsulfanyloctanoic acid)), has been developed to synthesize multigram quantities for enantiomeric separation. Using enantioenriched (S)-(−)-1,2,4-butanetr
Externí odkaz:
https://doaj.org/article/d45f776382614e7ca85134c3d5fb0c8c
Autor:
Clare M. Adams, Ramkrishna Mitra, Youcai Xiao, Peter Michener, Juan Palazzo, Allen Chao, Jitendra Gour, Joel Cassel, Joseph M. Salvino, Christine M. Eischen
Publikováno v:
Cancer Discovery. 13:1210-1229
Triple-negative breast cancers (TNBC) frequently inactivate p53, increasing their aggressiveness and therapy resistance. We identified an unexpected protein vulnerability in p53-inactivated TNBC and designed a new PROteolysis TArgeting Chimera (PROTA
Autor:
David E. Williams, Joel Cassel, Jin-Lin Zhu, Jian-Xiong Yang, Nicole J. de Voogd, Teatulohi Matainaho, Joseph M. Salvino, Yan Alexander Wang, Luis J. Montaner, Ian Tietjen, Raymond J. Andersen
Publikováno v:
Journal of Natural Products. 86:582-588
Autor:
Francesco F. De Pascali, Michael Ippolito, Nathan Hopfinger, Konstantin E. Komolov, Daniela K. Laurinavichyute, Leon A. Sakkal, Ajay P. Nayak, Poli AN. Reddy, Preston S. Donover, Melvin Reichman, Joseph M. Salvino, Raymond B. Penn, Roger S. Armen, Charles P. Scott, Jeffrey L. Benovic
Publikováno v:
ASPET 2023 Annual Meeting Abstract - Cellular and Molecular Pharmacology.