Zidovudine, didanosine, and zalcitabine in the treatment of HIV infection: meta-analyses of the randomised e vidence

Autor: A Gringeri, P Hartigan, R D'Aquila, J Yeo, L Dee, A Maeland, F Rousseau, J Darbyshire, M Flepp, T Merigan, H Chang, J Chodakewitz, C Farthing, K Stanley, G Van Weverling, L Mathiesen, R DeMasi, P Slade, H Melander, C Pettinelli, A Poppa, C Carbon, D Smith, M Seligmann, G Stingl, C Tierney, M Hughes, I Chalmers, M Foulkes, D Katzenstein, B Gazzard, L Struthers, Soriano, K Henry, J Veenstra, I Weller, S Danner, M Sande, L Deyton, E Sandstrom, M Fischl, A Phillips, D Richman, C Katlama, M Gartland, J Neaton, E King, A Collier, P Gotzsche, P Stoffels, G Rutherford, R Van der Broeck, D Allan, R Peto, J Rooney, J Ioannidis, W Duncan, F Antunes, S Schnittman, N Clendenin, J Lange, D Dixon, SK de Loes, A Babiker, E Cooper, D Hall, J Killen, P Volberding, A Hill, H McDade, A Meibohn, G Savidge, L Saravolatz, J Bruun, W Cameron, L Perrin, A Pinching, N Clumeck, M Simberkoff, P Mannucci, J Gatell, T Peto, M Heath-Chiozzi, M Salgo, G Skowron, R Van Leeuven, L Power, S Vella, J Phair, P Reiss, J Kahn, DeGruttola, D Winslow, M Myers, R Schooley, B Hirschel, S Hammer, R Leavitt, S Walker, G Collins, R Collins, J Leonard, RP Smith, D Abrams, J Mulder, J Hamilton, M Thompson, M Nessling, S Kravcik, Hiv Trialists' Collaborative Grp, D Cooper, A Breckenridge, F Goebel, J Dormont, J Weber, P Yeni, J Feinberg

Publikováno v: The Lancet. 353:2014-2025

Summary Background To assess the effects of zidovudine, didanosine, and zalcitabine on HIV disease progression and survival, we undertook meta-analyses of individual patient data and tabular data from all randomised trials that compared these agents.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9973fab0ba3628e3974bd59a2556e5f1
https://doi.org/10.1016/s0140-6736(98)12263-8

The SPICE study: 48-week activity of combinations of saquinavir soft gelatin and nelfinavir with and without nucleoside analogues. Study of Protease Inhibitor Combinations in Europe

Autor: G, Moyle, A, Pozniak, M, Opravil, N, Clumeck, J F, DelFraissy, M, Johnson, J, Pelgrom, J, Reynes, D, Vittecoq, P, DeLora, M, Salgo, F, Duff

Publikováno v: Journal of acquired immune deficiency syndromes (1999). 23(2)

To compare the efficacy and safety of saquinavir soft gelatin capsules (SQV-SGC) and nelfinavir (NFV), with or without two concomitant nucleoside reverse transcriptase inhibitors (NRTIs), in an exploratory objective to identify populations most likel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::af51b8c80836a2498302b18be2010a62
https://pubmed.ncbi.nlm.nih.gov/10737427

Evaluation of pharmacokinetics, safety, tolerance, and activity of combination of zalcitabine and zidovudine in stable, zidovudine-treated pediatric patients with human immunodeficiency virus infection. AIDS Clinical Trials Group Protocol 190 Team

Autor: S S, Bakshi, P, Britto, E, Capparelli, L, Mofenson, M G, Fowler, S, Rasheed, D, Schoenfeld, B, Zimmer, Y, Frank, R, Yogev, E, Jimenez, M, Salgo, G, Boone, S G, Pahwa

Publikováno v: The Journal of infectious diseases. 175(5)

A double-blind phase II trial compared zalcitabine (0.03 mg/kg/day) in combination with zidovudine (720 mg/m2/day) and zidovudine monotherapy in 250 clinically stable, previously zidovudine-treated, human immunodeficiency virus-infected children. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::67b0731f4d7931c6bf42c9c40b4b2fc2
https://pubmed.ncbi.nlm.nih.gov/9129064

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