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HIGH-LEVEL PORCINE ENDOTHELIAL CELL EXPRESSION OF ??(1,2)-FUCOSYLTRANSFERASE REDUCES HUMAN MONOCYTE ADHESION AND ACTIVATION1

Autor: Silviu Itescu, Sorina Tugulea, Robert E. Michler, Ian F. C. McKenzie, John H. Artrip, M. S. Sandrin, Niloo M. Edwards, Pawel Kwiatkowski, Katherine Lietz

Publikováno v: Transplantation. 67:219-226

Background. Monocyte binding to and activation by human endothelium requires a number of interactions, including those involving sialylated endothelial cell ligands. As porcine endothelial cell transfection with α(1,2)-fucosyltransferase has been sh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f71243ebb4cb03d20ea31af56f554853
https://doi.org/10.1097/00007890-199901270-00006

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Isolation and characterization of cDNA clones for the mouse thymocyte B cell antigen (ThB)

Autor: T P Gumley, I F McKenzie, C A Kozak, M S Sandrin

Publikováno v: The Journal of Immunology. 149:2615-2618

The Thb locus is responsible for the expression of 15-kDa phosphatidyl inositol anchored molecules (ThB) on murine thymocytes and B cells. Thb expression as detected with mAb is polymorphic on B cells with two alleles, Thbh and Thb1 responsible for t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::566f01e6ba92442dca2e505007b96e38
https://doi.org/10.4049/jimmunol.149.8.2615

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Isolation and characterization of cDNA clones for mouse Ly-9

Autor: M S Sandrin, T P Gumley, M M Henning, H A Vaughan, L J Gonez, J A Trapani, I F McKenzie

Publikováno v: The Journal of Immunology. 149:1636-1641

We describe the production and characterization of a mouse mAb, S-450-33.2, recognizing the Ly-9.2 specificity. This mAb was used to purify Ly-9 molecules from lymphoid cell lines, and the amino-terminal amino acids were determined. The mAb was also

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d4b81ddd5c0ac91dc86d0b9587512c9a
https://doi.org/10.4049/jimmunol.149.5.1636

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Effect of IL-4 deletion on cardiac allograft survival in the BALB/c to 129Sv × C57BL/6 strain combination

Autor: Ian F. C. McKenzie, M. S. Sandrin, LJ Murray-Segal, Patricia L Mottram, Yu Qin Li, W-R Han

Publikováno v: Immunology and Cell Biology. 76:563-565

To investigate the effect of IL-4 deletion on cardiac allograft survival, vascularized BALB/c cardiac allografts were placed in C57BL/6, 129Sv x C57BL/6 (IL-4 +/+) or 129Sv x C57BL/6 IL-4 knockout mice (IL-4-/-). Untreated recipients rejected allogra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efba3fd5717e9879e44b0c2abf991fe5
https://doi.org/10.1046/j.1440-1711.1998.00784.x

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Evidence for structurally conserved recognition of the major carbohydrate xenoantigen by natural antibodies

Autor: P A, Ramsland, W, Farrugia, E, Yuriev, A B, Edmundson, M S, Sandrin

Publikováno v: Cellular and molecular biology (Noisy-le-Grand, France). 49(2)

Natural or preformed antibodies that react with oligosaccharides bearing terminal galactose-alpha(1,3)-galactose [Gal alpha(1,3)Gal] stuctures are present in the sera of all humans. Antibodies against Gal alpha(1,3)Gal epitopes initiate hyperacute re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::387c713ea697fa37cf6e321cca07881d
https://pubmed.ncbi.nlm.nih.gov/12887109

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Tolerance in baboon kidney transplantation with total lymphoid irradiation (TLI) and anti-CD3/CD4-idarubicin conjugates

Autor: J A, Myburgh, J A, Smit, G A, Pieterz, S, Ling, M S, Sandrin, I F, McKenzie

Publikováno v: Transplantation. 72(6)

We previously reported the induction of transplantation tolerance by a modified wide field method of pretransplant total lymphoid irradiation (TLI), cumulative dose 800 cGy, given as 80 or 100 cGy fractions twice/week, in approximately one-third of c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::33e34f58391e4fe4a6d82d8b1fdddb00
https://pubmed.ncbi.nlm.nih.gov/11579315

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Characteristics of immunoglobulin gene usage of the xenoantibody binding to gal-alpha(1,3)gal target antigens in the gal knockout mouse

Autor: S, Nozawa, P X, Xing, G D, Wu, E, Gochi, M, Kearns-Jonker, J, Swensson, V A, Starnes, M S, Sandrin, I F, McKenzie, D V, Cramer

Publikováno v: Transplantation. 72(1)

Natural antibodies that react with galactose-alpha(1,3)galactose [galalpha(1,3)gal] carbohydrate epitopes exist in humans and Old World primates because of the inactivation of the alpha1,3-galactosyltransferase (alpha1,3GT) gene in these species and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::383b2bdd4ad91102a705eabaf92fb52d
https://pubmed.ncbi.nlm.nih.gov/11468550

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Inhibition of hyperacute transplant rejection by soluble proteins with the functional domains of CD46 and FcgammaRII

Autor: M B, Lanteri, M S, Powell, D, Christiansen, Y Q, Li, M, Hogarth, M S, Sandrin, I F, Mckenzie, B E, Loveland

Publikováno v: Transplantation. 69(6)

Recombinant soluble forms of complement regulatory molecules, including the human complement regulatory protein CD46 (rsCD46), have been shown to inhibit hyperacute transplant rejection (HAR) and protect against complement-mediated inflammatory tissu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::242b96339f7e2ffd4a520ba8f9e8e91a
https://pubmed.ncbi.nlm.nih.gov/10762202

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