Zobrazeno 1 - 10
of 11
pro vyhledávání: '"M S Irwin"'
Autor:
F D Miller, M S Irwin
Publikováno v:
Cell Death & Differentiation. 11:S17-S22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc401ccc6fe326230cd0784854fa00a8
https://doi.org/10.1038/sj.cdd.4401452
https://doi.org/10.1038/sj.cdd.4401452
Publikováno v:
Journal of Hand Surgery. 22:308-316
Cold intolerance can be severe and debilitating following injury to the hand. Little is known about its natural history and factors predicting symptom severity. We looked retrospectively at upper limb peripheral nerve injuries over a 12-year period.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b063acf7f8357b317d2fbafd6b5e1be
https://doi.org/10.1016/s0266-7681(97)80392-0
https://doi.org/10.1016/s0266-7681(97)80392-0
Publikováno v:
Current drug targets. 11(6)
The p53-family of transcription factors consists of three genes - p53, p63, and p73 - that share significant structural and functional similarities. Although these genes encode multiple variants that have opposing functions in cancer biology, the ful
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52755152799bacd223e04cecbbb40224
https://pubmed.ncbi.nlm.nih.gov/20298155
https://pubmed.ncbi.nlm.nih.gov/20298155
Publikováno v:
Oncogene. 27(7)
Nutlin-3, a small molecule inhibitor, activates p53 by disrupting p53-HDM2 association. In this study, we found that Nutlin-3 suppressed cell growth and induced apoptosis in the absence of wild-type p53, suggesting a p53-independent mechanism for Nut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08aef2e10d3d18c5ea0f0de1625ffda3
https://pubmed.ncbi.nlm.nih.gov/17700533
https://pubmed.ncbi.nlm.nih.gov/17700533
Autor:
M S, Irwin, W G, Kaelin
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 12(7)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c817e77586dc87f67744e08517dd4803
https://pubmed.ncbi.nlm.nih.gov/11457731
https://pubmed.ncbi.nlm.nih.gov/11457731
Autor:
M S, Irwin, W G, Kaelin
Publikováno v:
Apoptosis : an international journal on programmed cell death. 6(1-2)
The most recently identified members of the p53 family, p63 and p73, share certain structural and functional similarities with p53. Both p63 and p73 can bind to canonical p53-DNA-binding sites, transactivate the promoters of known p53 target genes an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4a47a7dc8d0260fc456373afc4dff928
https://pubmed.ncbi.nlm.nih.gov/11321038
https://pubmed.ncbi.nlm.nih.gov/11321038
Publikováno v:
British Journal of Plastic Surgery. 44:312-314
A patient with an amelanotic lentigo malignant melanoma is presented which manifested itself initially as an erythematous flare with the subsequent development of nodules. The diagnosis was only made histologically. A computer search of the literatur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43758394b40c2fb2debb925f8b7a1921
https://doi.org/10.1016/0007-1226(91)90080-4
https://doi.org/10.1016/0007-1226(91)90080-4
Autor:
M. S. Irwin, Sandra Fuertes-Alvarez, A. Blanch, Jens Christian Schwamborn, Anna-Lena Hillje, L. Gonzalez-Cano, R. W. Ian, Maria C. Marin, Margarita M. Marques
Publikováno v:
Cell Death & Disease
The p73 transcription factor is one of the members of the p53 family of tumor suppressors with unique biological functions in processes like neurogenesis, embryonic development and differentiation. For this reason, p73 activity is tightly regulated b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1e95336f55f3280908da20cd4441ad9
https://doi.org/10.1038/cddis.2013.224
https://doi.org/10.1038/cddis.2013.224
Nature and mechanism of peripheral nerve damage in an experimental model of non-freezing cold injury
Autor:
M S, Irwin
Publikováno v:
Annals of the Royal College of Surgeons of England. 78(4)
Non-freezing cold injury (NFCI), so called trench foot, is a condition characterised by a peripheral neuropathy, developing when the extremities are exposed for prolonged periods to wet conditions at temperatures just above freezing. Classically, mil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1e75a80de043cf0b20f3cde7385ff32f
https://pubmed.ncbi.nlm.nih.gov/8712655
https://pubmed.ncbi.nlm.nih.gov/8712655
Autor:
M S, Irwin
Publikováno v:
RN. 59(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7e1acc14f7526627c0a23bb8482c7db0
https://pubmed.ncbi.nlm.nih.gov/8685615
https://pubmed.ncbi.nlm.nih.gov/8685615