Zobrazeno 1 - 10
of 32
pro vyhledávání: '"M S Christian"'
Publikováno v:
The Journal of Maternal-Fetal & Neonatal Medicine. 20:89-112
A large National Institutes of Health (NIH) study showed that pharmacy-compounded 17alpha-hydroxyprogesterone caproate (17-OHP-C) reduced the incidence of preterm birth. The study results included a signal that 17-OHP-C may be associated with an incr
Publikováno v:
Journal of the American College of Toxicology. 15:349-370
Triethylene glycol monomethyl ether (TGME) was administered orally via gavage stomach tube to mated Caesarean delivered (CD) rats and artificially inseminated New Zealand white rabbits on days 6–15 and 6–18 of gestation, respectively, at dose lev
Publikováno v:
Journal of the American College of Toxicology. 14:119-128
Clarified slurry oil (CSO, CAS #64741–62-4; also termed carbon black oil), a residual product from the fluidized catalytic cracker in petroleum refining, has the potential to be absorbed through the skin. The reproductive toxicity of CSO in male an
Publikováno v:
Toxicological Sciences. 28:34-40
Pregnant CD rats were exposed dermally to 0.05, 1, 10, 50, and 250 mg/kg/day of Clarified Slurry Oil (CSO) on Days 0-19 of gestation to determine its potential developmental toxicity. Untreated and vehicle controls were included in the study. Day 20
Autor:
M. S. Christian
Publikováno v:
Journal of the American College of Toxicology. 5:161-180
The Chemical Manufacturers Association has an ongoing project to summarize information required to evaluate various approaches to assessment of reproductive hazards in the workplace. The information presented in this manuscript was generated as a par
Autor:
Rochelle W. Tyl, H. V. Levinsky, David W. Gaylor, W. Setzer, M. Ottley, R. D. Costlow, Bryan D. Hardin, J. L. Schardein, V. Frankos, R. S. Filler, M. S. Christian, K. S. Khera, W. Hart, John M. Rogers, V. M. Chinchilli, Bernard A. Schwetz, J. Buelke-Sam, S. Dapson, Q. Q. Bui, J. Parker, S. Perlin
Publikováno v:
Teratogenesis, Carcinogenesis, and Mutagenesis. 7:321-327
Autor:
E. M. Johnson, M. S. Christian
Publikováno v:
Journal of the American College of Toxicology. 3:431-434
The most widely used developmental toxicity safety evaluation is the Segment II protocol executed in rats and rabbits. It has come to be called the “teratology” study, even though it is not designed to produce terata and is not the optimal means
Publikováno v:
Teratogenesis, Carcinogenesis, and Mutagenesis. 7:65-71
The Chernoff-Kavlock assay was initially designed to identify developmental toxins within a relatively short time frame, using a mammalian system. Although it has been used for initial prioritization of multiple agents studied concurrently or for dos
Publikováno v:
Toxicological Sciences. 13:359-365
The developmental toxicity (embryofetotoxicity or teratogenicity) and maternal toxicity of butoxypropanol, a propylene glycol ether, was evaluated in New Zealand White rabbits. Dosages of 0 (water), 10, 40 or 100 mg/kg/day, selected on the basis of t