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pro vyhledávání: '"M S, Vala"'
Autor:
A, Bedi, J P, Barber, G C, Bedi, W S, el-Deiry, D, Sidransky, M S, Vala, A J, Akhtar, J, Hilton, R J, Jones
Publikováno v:
Blood. 86:1148-1158
A critical determinant of the efficacy of antineoplastic therapy is the response of malignant cells to DNA damage induced by anticancer agents. The p53 tumor-suppressor gene is a critical component of two distinct cellular responses to DNA damage, th
Autor:
R J, Jones, M I, Collector, J P, Barber, M S, Vala, M J, Fackler, W S, May, C A, Griffin, A L, Hawkins, B A, Zehnbauer, J, Hilton, O M, Colvin, S J, Sharkis
Publikováno v:
Blood. 88(2)
The classical definition of lymphohematopoietic stem cells (LHSC), the most primitive progenitors of all blood cells, requires that they have the capacity for self-renewal and for the long-term production of all blood cell lineages. However, other ch
Autor:
A, Bedi, C A, Griffin, J P, Barber, M S, Vala, A L, Hawkins, S J, Sharkis, B A, Zehnbauer, R J, Jones
Publikováno v:
Cancer research. 54(21)
Expression of the BCR-ABL chimeric gene in chronic myeloid leukemia results in the inhibition of apoptosis, a genetically programmed process of autonomous cell death. BCR-ABL and other genetic factors that suppress apoptosis confer cross-resistance t