Zobrazeno 1 - 10
of 39
pro vyhledávání: '"M S, Tockman"'
Autor:
Ronald G. Crystal, J. M. Stocks, J. Wittes, Mark D. Schluchter, James K. Stoller, B. Burrows, M. S. Tockman, M. C. Wu, A. S. Buist, A. Rothgeb, A. B. Cohen, R. A. Robbins, Herbert Y. Reynolds, Z. Bengali, G. L. Snider, K. Detre, A. F. Barker, R. J. Fallat, C. E. Vreim
Publikováno v:
Chest. 106:1223-1232
Autor:
M S, Tockman
Publikováno v:
IARC scientific publications. 154
Even after smoking cessation, genetic damage in the airways epithelium may lead to focal progression of lung carcinogenesis. Some centres now report as many new lung cancer cases among former smokers as among current smokers. Chemoprevention is a pot
Autor:
D, Ratnasinghe, S X, Yao, J A, Tangrea, Y L, Qiao, M R, Andersen, M J, Barrett, C A, Giffen, Y, Erozan, M S, Tockman, P R, Taylor
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 10(2)
We explored the association between polymorphisms of the DNA repair gene XRCC1 (codons 194, 280, and 399) and lung cancer risk in a case-control study nested within a cohort of tin miners. Cases were those diagnosed with lung cancer over 6 years of f
Autor:
L, Xu, J, Chow, J, Bonacum, C, Eisenberger, S A, Ahrendt, M, Spafford, L, Wu, S M, Lee, S, Piantadosi, M S, Tockman, D, Sidransky, J, Jen
Publikováno v:
International journal of cancer. 91(2)
We surveyed the occurrence of novel alleles at microsatellite sequences in non-small cell lung cancers (NSCLC) using 61 tetranucleotide repeat markers. The presence of at least one new allele, consistent with microsatellite instability (MSI), was obs
Publikováno v:
Cancer. 89
The current mortality rate for lung cancer exceeds 85%, as it has for the last 3 decades. This statistic reflects the utility of the major diagnostic tool that has been used during this period to diagnose lung cancer: the chest X-ray. The overwhelmin
Autor:
M S, Tockman, J L, Mulshine
Publikováno v:
Chest surgery clinics of North America. 10(4)
These sputum tests offer great promise in determining a molecular diagnosis of lung cancer far in advance of clinical presentation. Any or all of these tests could be incorporated into the routine management of individuals at risk for developing prim
Autor:
D, Ratnasinghe, J A, Tangrea, M R, Forman, T, Hartman, E W, Gunter, Y L, Qiao, S X, Yao, M J, Barett, C A, Giffen, Y, Erozan, M S, Tockman, P R, Taylor
Publikováno v:
Cancer causescontrol : CCC. 11(2)
To evaluate the association of prediagnostic serum antioxidants and lung cancer risk we conducted a case-control study nested in an occupational cohort of tin miners.Male workers free of cancer enrolled in the cohort. During up to 6 years of follow-u
Autor:
M S, Tockman, J L, Mulshine, S, Piantadosi, Y S, Erozan, P K, Gupta, J C, Ruckdeschel, P R, Taylor, T, Zhukov, W H, Zhou, Y L, Qiao, S X, Yao
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 3(12 Pt 1)
The United States lung cancer epidemic has not yet been controlled by present prevention and treatment strategies. Overexpression of a Mr 31,000 protein, heterogeneous nuclear ribonucleoprotein (hnRNP) A2/B1, had shown promise as a marker of lung can
Autor:
Y L, Qiao, M S, Tockman, L, Li, Y S, Erozan, S X, Yao, M J, Barrett, W H, Zhou, C A, Giffen, X C, Luo, P R, Taylor
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 6(11)
We initiated the present study to evaluate the accuracy of a new epithelial biomarker of early lung cancer. We tested the hypothesis that expression of a tumor-associated antigen by exfoliated sputum epithelial cells has greater accuracy (sensitivity
Autor:
F M, Scott, R, Modali, T A, Lehman, M, Seddon, K, Kelly, E C, Dempsey, V, Wilson, M S, Tockman, J L, Mulshine
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 3(3)
A high frequency of K-ras mutations may indicate preneoplastic changes in the bronchial epithelium as a result of genotoxic injury. With the use of sensitive detection techniques, we report a higher prevalence of K-ras mutations in bronchoalveolar la