Výsledky vyhledávání - "M S, Tockman"

Lung cancer: chemoprevention and intermediate effect markers

Autor: M S, Tockman

Publikováno v: IARC scientific publications. 154

Even after smoking cessation, genetic damage in the airways epithelium may lead to focal progression of lung carcinogenesis. Some centres now report as many new lung cancer cases among former smokers as among current smokers. Chemoprevention is a pot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a765adedb238a219c110d743a2757d94
https://pubmed.ncbi.nlm.nih.gov/11220665

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Polymorphisms of the DNA repair gene XRCC1 and lung cancer risk

Autor: D, Ratnasinghe, S X, Yao, J A, Tangrea, Y L, Qiao, M R, Andersen, M J, Barrett, C A, Giffen, Y, Erozan, M S, Tockman, P R, Taylor

Publikováno v: Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 10(2)

We explored the association between polymorphisms of the DNA repair gene XRCC1 (codons 194, 280, and 399) and lung cancer risk in a case-control study nested within a cohort of tin miners. Cases were those diagnosed with lung cancer over 6 years of f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0894fc8217f3643bff959d7c8698f849
https://pubmed.ncbi.nlm.nih.gov/11219768

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Microsatellite instability at AAAG repeat sequences in respiratory tract cancers

Autor: L, Xu, J, Chow, J, Bonacum, C, Eisenberger, S A, Ahrendt, M, Spafford, L, Wu, S M, Lee, S, Piantadosi, M S, Tockman, D, Sidransky, J, Jen

Publikováno v: International journal of cancer. 91(2)

We surveyed the occurrence of novel alleles at microsatellite sequences in non-small cell lung cancers (NSCLC) using 61 tetranucleotide repeat markers. The presence of at least one new allele, consistent with microsatellite instability (MSI), was obs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c3e7da480324512ac35cc282f1ad6ad7
https://pubmed.ncbi.nlm.nih.gov/11146445

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Considerations in developing successful, population-based molecular screening and prevention of lung cancer

Autor: J L, Mulshine, L M, De Luca, R L, Dedrick, M S, Tockman, R, Webster, M E, Placke

Publikováno v: Cancer. 89

The current mortality rate for lung cancer exceeds 85%, as it has for the last 3 decades. This statistic reflects the utility of the major diagnostic tool that has been used during this period to diagnose lung cancer: the chest X-ray. The overwhelmin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::843399d03445bd1b0bce87d7ab238b7f
https://pubmed.ncbi.nlm.nih.gov/11147628

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The early detection of occult lung cancer

Autor: M S, Tockman, J L, Mulshine

Publikováno v: Chest surgery clinics of North America. 10(4)

These sputum tests offer great promise in determining a molecular diagnosis of lung cancer far in advance of clinical presentation. Any or all of these tests could be incorporated into the routine management of individuals at risk for developing prim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::23a611e6535276a9f82e37f09547be2e
https://pubmed.ncbi.nlm.nih.gov/11091923

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Serum tocopherols, selenium and lung cancer risk among tin miners in China

Autor: D, Ratnasinghe, J A, Tangrea, M R, Forman, T, Hartman, E W, Gunter, Y L, Qiao, S X, Yao, M J, Barett, C A, Giffen, Y, Erozan, M S, Tockman, P R, Taylor

Publikováno v: Cancer causescontrol : CCC. 11(2)

To evaluate the association of prediagnostic serum antioxidants and lung cancer risk we conducted a case-control study nested in an occupational cohort of tin miners.Male workers free of cancer enrolled in the cohort. During up to 6 years of follow-u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b027d2e368d8a83dc47846ad51e1cc8d
https://pubmed.ncbi.nlm.nih.gov/10710196

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Prospective detection of preclinical lung cancer: results from two studies of heterogeneous nuclear ribonucleoprotein A2/B1 overexpression

Autor: M S, Tockman, J L, Mulshine, S, Piantadosi, Y S, Erozan, P K, Gupta, J C, Ruckdeschel, P R, Taylor, T, Zhukov, W H, Zhou, Y L, Qiao, S X, Yao

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 3(12 Pt 1)

The United States lung cancer epidemic has not yet been controlled by present prevention and treatment strategies. Overexpression of a Mr 31,000 protein, heterogeneous nuclear ribonucleoprotein (hnRNP) A2/B1, had shown promise as a marker of lung can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a2b5b7b5796e7e2a005b569a0a071b6e
https://pubmed.ncbi.nlm.nih.gov/10778995

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