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Autor:
B S, Wong, C, Clive, S J, Haswell, R A, Williamson, D R, Burton, P, Gambetti, M S, Sy, I M, Jones, D R, Brown
Publikováno v:
Biochemical and Biophysical Research Communications. 269:726-731
The pathology of human prion diseases is affected by polymorphism at amino acid residue 129 of the prion protein gene. Recombinant mouse prion proteins mimicking either form of the polymorphism were prepared to examine their effect on the conformatio
Publikováno v:
The Journal of Immunology. 163:4224-4231
Proteins involved in class I MHC (MHC-I) Ag processing, such as the TAP, are deficient in some human tumor cells. This suggests that antitumor responses by CD8 T cells provide selection pressure to favor outgrowth of cells with defective processing o
Publikováno v:
The Journal of Immunology. 159:2702-2711
Receptor oligomerization is important for ligand binding and signal transduction. CD44 is a transmembrane protein present on many cell types. One of the ligands for CD44 is hyaluronic acid (HA). HA binding activity of CD44 is linked to cellular activ
Publikováno v:
The Journal of Immunology. 150:1619-1628
T cells are major mediators of graft rejection and many autoimmune diseases. During the Ag recognition process, T cells often become activated. We tested the hypothesis that an anti-CD3:anti-CD25 (CD3,25) bispecific mAb (BSMAB) can effectively and se
Autor:
C Shen, Bo Shen, Tomas Ganz, Terry Gramlich, E Reynoso, Charles L. Bevins, M S Sy, R Li, Jason T. Connor, Edith Porter, H K Rho, Dipankar Ghosh, Adrian H. Ormsby, Judith A. Drazba
Publikováno v:
Shen, B; Porter, E M; Reynoso, E; Shen, C; Ghosh, D; Connor, J T; et al.(2005). Human defensin 5 expression in intestinal metaplasia of the upper gastrointestinal tract. Journal of Clinical Pathology, 58(7), 687-694. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/8wj6w6zt
Background: Upper gastrointestinal tract intestinal metaplasia (IM) is termed Barrett’s oesophagus (BO) or gastric intestinal metaplasia (GIM), depending on its location. BO and GIM are associated with chemical exposure resulting from gastro–oeso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a70d4e39821a6fafdf180b4b4a79b940
http://www.escholarship.org/uc/item/8wj6w6zt
http://www.escholarship.org/uc/item/8wj6w6zt
Autor:
B S, Wong, D R, Brown, T, Pan, M, Whiteman, T, Liu, X, Bu, R, Li, P, Gambetti, J, Olesik, R, Rubenstein, M S, Sy
Publikováno v:
Journal of neurochemistry. 79(3)
Prion diseases are characterized by the conversion of the normal cellular prion protein (PrP(C)) into a pathogenic isoform (PrP(Sc)). PrP(C) binds copper, has superoxide dismutase (SOD)-like activity in vitro, and its expression aids in the cellular
Publikováno v:
Panminerva medica. 43(4)
Prion diseases are not only genetic or sporadic neurodegenerative disorders, but more important, they are transmissible diseases. The etiological agent in these unprecedented diseases is believed to be prion protein (PrP), which undergoes post-transl