Zobrazeno 1 - 10
of 17
pro vyhledávání: '"M S, Pasternack"'
Publikováno v:
The Journal of Immunology. 156:1989-1996
We have generated two IgG murine mAbs that recognize native human haptoglobin (Hp). These mAbs, 3A8 and 4B2, efficiently bind to the Hp complex regardless of the serum donor's phenotype. The specificity of mAb 3A8 was confirmed by immunoaffinity puri
Publikováno v:
The Journal of Immunology. 149:1265-1270
There has been considerable recent interest in the possible role of extracellular ATP in cell-mediated cytotoxicity. To investigate the similarities and differences between ATP-mediated lysis and CTL-mediated lysis, we studied in detail the ATP-media
Autor:
M S, Pasternack
Publikováno v:
Current clinical topics in infectious diseases. 17
Autor:
N G, Guerina, H W, Hsu, H C, Meissner, J H, Maguire, R, Lynfield, B, Stechenberg, I, Abroms, M S, Pasternack, R, Hoff, R B, Eaton
Publikováno v:
The New England journal of medicine. 330(26)
Most infants with congenital Toxoplasma gondii infection have no symptoms at birth, but many will have retinal disease or neurologic abnormalities later in life. Early detection and treatment of congenital toxoplasmosis may reduce these sequelae.In M
Publikováno v:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 17(2)
An experience with wound sepsis due to Flavobacterium meningosepticum in two pediatric burn patients is described. This organism, which is typically found in water and soil, generally has low pathogenicity but may become clinically important in immun
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 149(4)
There has been considerable recent interest in the possible role of extracellular ATP in cell-mediated cytotoxicity. To investigate the similarities and differences between ATP-mediated lysis and CTL-mediated lysis, we studied in detail the ATP-media
Publikováno v:
The Journal of biological chemistry. 266(22)
The physiologic substrates of cytotoxic T lymphocyte granule-associated serine esterases (referred to hereafter as proteases or "granzymes"), and the role of these enzymes in cell-mediated activity remain unclear. We have developed an assay for possi
Publikováno v:
The Journal of Immunology. 134:2456-2461
We have studied the activation signals that regulate interferon-gamma (IFN-gamma) secretion from murine cytotoxic T lymphocytes (CTL) upon binding mitogen or antigen. CTL clones were found to require at least 1 hr of stimulation with concanavalin A (
Publikováno v:
The Journal of Immunology. 133:277-280
We have examined the potential of murine cytotoxic T lymphocytes (CTL) to synthesize both IFN-gamma and IFN-alpha, beta by using three cloned antigen-reactive CTL lines. These lines, which produce IFN-gamma in an antigen-specific manner or after stim
Publikováno v:
The Journal of Immunology. 131:2477-2483
N-alpha-tosyl-L-lysyl-chloromethyl-ketone (TLCK), an irreversible inhibitor of trypsin-like serine proteases, is a potent, nontoxic inhibitor of cytotoxic T lymphocyte (CTL) activity with half-maximal inhibition of an alloreactive CTL clone occurring