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Publikováno v:
Clinical and Experimental Immunology. 113:367-372
SUMMARY Autoantibodies to a 64-kD protein and a 40-kD tryptic fragment from pancreatic islets have been detected at high frequency in the sera of patients with insulin-dependent diabetes mellitus (IDDM). IA-2, a newly isolated transmembrane protein t
Publikováno v:
The Journal of Immunology. 159:3662-3667
IA-2 and IA-2 beta are major autoantigens in insulin-dependent diabetes mellitus (IDDM) and the precursors, respectively, of a 40-and 37-kDa tryptic fragment that reacts with IDDM sera. In the present study, by amino acid sequencing of recombinant IA
Publikováno v:
Diabetes. 46:1270-1275
Publikováno v:
Diabetes. 46:40-43
Publikováno v:
Applied Artificial Intelligence. 6:315-330
In this article, we present a case-based-reasoning approach for the solution of complex manufacturing problems. We describe an application of this methodology to the development of an automated system for weld-process design. We also describe the gen
Autor:
M.-S. Lan, R.M. Panos
Publikováno v:
IEEE Expert. 5:65-73
One of the steps in preparing newspaper presses for a new printing run is composing a lineup. A newspaper lineup arranges the printing run's many image plates among the numerous press locations where images are transferred to paper; this is both a co
Autor:
Q-Y, Chen, N, Jackson, A, Vargas, S, Chalew, J, Rao, M, Batzer, M S, Lan, Y-H, Chang, M, Mokhashi, D, Liu
Publikováno v:
Tissue antigens. 62(5)
CD1d presents lipid antigen to a conserved population of natural killer (NK) T cells, which participate in host immune defense, tumor cell rejection and suppression of autoimmunity. The levels of human CD1d expression vary significantly between indiv
Publikováno v:
The Biochemical journal. 354(Pt 3)
Using a cross-linking approach, we have recently demonstrated that radiolabelled model peptides or misfolded proteins specifically interact in vitro with two members of the protein disulphide- isomerase family, namely PDI and PDIp, in a crude extract
Autor:
Q Y, Chen, D, Nadell, X Y, Zhang, A, Kukreja, Y J, Huang, J, Wise, F, Svec, R, Richards, K E, Friday, A, Vargas, R, Gomez, S, Chalew, M S, Lan, Y, Tomer, N K, Maclaren
Publikováno v:
The Journal of clinical endocrinology and metabolism. 85(4)
Information on genetic susceptibility to Graves' disease in African Americans is limited. We studied DRB1, DQB1, DRB3 subtypes, DQA1*0501, DQA1*0201, and CTLA-4 polymorphisms in 49 African American patients with adult onset Graves' disease and 47 rac