Výsledky vyhledávání

Expression, characterization, processing and immunogenicity of an insulin-dependent diabetes mellitus autoantigen, IA-2, in Sf-9 cells

Autor: M S Lan, H Xie, Abner Louis Notkins, Y J Deng

Publikováno v: Clinical and Experimental Immunology. 113:367-372

SUMMARY Autoantibodies to a 64-kD protein and a 40-kD tryptic fragment from pancreatic islets have been detected at high frequency in the sera of patients with insulin-dependent diabetes mellitus (IDDM). IA-2, a newly isolated transmembrane protein t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea96025d34796cb5821306268afc9911
https://doi.org/10.1046/j.1365-2249.1998.00676.x

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Autoantibodies to IA-2 and IA-2 beta in insulin-dependent diabetes mellitus recognize conformational epitopes: location of the 37- and 40-kDa fragments determined

Autor: H Xie, B Zhang, Y Matsumoto, Q Li, A L Notkins, M S Lan

Publikováno v: The Journal of Immunology. 159:3662-3667

IA-2 and IA-2 beta are major autoantigens in insulin-dependent diabetes mellitus (IDDM) and the precursors, respectively, of a 40-and 37-kDa tryptic fragment that reacts with IDDM sera. In the present study, by amino acid sequencing of recombinant IA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b4287e5befdd7a727ae90d0260f74b96
https://doi.org/10.4049/jimmunol.159.7.3662

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Value of antibodies to islet protein tyrosine phosphatase-like molecule in predicting type 1 diabetes

Autor: M. Hawa, R. Rowe, M. S. Lan, A. L. Notkins, P. Pozzilli, M. R. Christie, R. D. Leslie

Publikováno v: Diabetes. 46:1270-1275

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8ebb636f80b49192d668d5ead2cb5579
https://doi.org/10.2337/diabetes.46.8.1270

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Autoantibodies to IA-2 in IDDM: location of major antigenic determinants

Autor: B. Zhang, M. S. Lan, A. L. Notkins

Publikováno v: Diabetes. 46:40-43

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8aace022c091ff3a3b37c90b7185fb66
https://doi.org/10.2337/diabetes.46.1.40

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Akademický článek

A Novel Ubiquitin Ligase Adaptor PTPRN Suppresses Seizure Susceptibility through Endocytosis of NaV1.2 Sodium Channels.

Autor: Wang, Yifan^1,2 (AUTHOR), Yang, Hui^1,2 (AUTHOR), Li, Na^1,2 (AUTHOR), Wang, Lili^1,2 (AUTHOR), Guo, Chang^1,2 (AUTHOR), Ma, Weining³ (AUTHOR), Liu, Shiqi^1,2 (AUTHOR), Peng, Chao^1,2 (AUTHOR), Chen, Jiexin^1,2 (AUTHOR), Song, Huifang^1,2 (AUTHOR), Chen, Hedan^1,2 (AUTHOR), Ma, Xinyue^1,2 (AUTHOR), Yi, Jingyun^1,2 (AUTHOR), Lian, Jingjing^1,2 (AUTHOR), Kong, Weikaixin^1,2 (AUTHOR), Dong, Jie^1,2 (AUTHOR), Tu, Xinyu^1,2 (AUTHOR), Shah, Mala⁴ (AUTHOR), Tian, Xin⁵ (AUTHOR) xintian@cqmu.edu.cn, Huang, Zhuo^1,2 (AUTHOR) huangz@hsc.pku.edu.cn

Publikováno v: Advanced Science. 8/7/2024, Vol. 11 Issue 29, p1-20. 20p.

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Akademický článek

High baseline perivascular space volume in basal ganglia is associated with attention and executive function decline in Parkinson's disease.

Autor: Foreman, Ryan Patrick^1,2 (AUTHOR), Donahue, Erin Kaye¹ (AUTHOR), Duran, Jared Joshua¹ (AUTHOR), Schiehser, Dawn M.^3,4 (AUTHOR), Petkus, Andrew¹ (AUTHOR), O'Neill, Joseph⁵ (AUTHOR), Holschneider, Daniel Phillip⁶ (AUTHOR), Choupan, Jeiran⁷ (AUTHOR), Van Horn, John Darrell^8,9 (AUTHOR), Bayram, Ece¹⁰ (AUTHOR), Litvan, Irene¹⁰ (AUTHOR), Jakowec, Michael Walter² (AUTHOR), Petzinger, Giselle Maria¹ (AUTHOR) petzinge@med.usc.edu

Publikováno v: Brain & Behavior. Jul2024, Vol. 14 Issue 7, p1-7. 7p.

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A CASE-BASED REASONING APPROACH TO AUTOMATED WELD-PROCESS DESIGN

Autor: D. R. Partridge, L. J. O'Connor, J. M. F. Lee, M. S. Lan

Publikováno v: Applied Artificial Intelligence. 6:315-330

In this article, we present a case-based-reasoning approach for the solution of complex manufacturing problems. We describe an application of this methodology to the development of an automated system for weld-process design. We also describe the gen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::71551a8fc59a0e11da8e4587ae6818b2
https://doi.org/10.1080/08839519208949958

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Printing press configuration-a knowledge-based approach

Autor: M.-S. Lan, R.M. Panos

Publikováno v: IEEE Expert. 5:65-73

One of the steps in preparing newspaper presses for a new printing run is composing a lineup. A newspaper lineup arranges the printing run's many image plates among the numerous press locations where images are transferred to paper; this is both a co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::807ee04d66f6d8016884e79356c2ef65
https://doi.org/10.1109/64.50858

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Identification of three genomic haplotypes 5' to the human CD1D gene and their distribution in four ethnic groups

Autor: Q-Y, Chen, N, Jackson, A, Vargas, S, Chalew, J, Rao, M, Batzer, M S, Lan, Y-H, Chang, M, Mokhashi, D, Liu

Publikováno v: Tissue antigens. 62(5)

CD1d presents lipid antigen to a conserved population of natural killer (NK) T cells, which participate in host immune defense, tumor cell rejection and suppression of autoimmunity. The levels of human CD1d expression vary significantly between indiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6db4fb5dff417e8cf676b4347586f0ac
https://pubmed.ncbi.nlm.nih.gov/14617053

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