Zobrazeno 1 - 10
of 39
pro vyhledávání: '"M S, Drutskaya"'
Autor:
N. R. Chicherina, E. A. Gorshkova, E. A. Myachev, A. S. Yakovleva, A. M. Litvinova, O. A. Namakanova, R. V. Zvartsev, S. A. Nedospasov, M. S. Drutskaya
Publikováno v:
Медицинская иммунология, Vol 26, Iss 5, Pp 919-926 (2024)
Chronic inflammation caused by overexpression of IL-6 underlies a number of pathological conditions Mouse models of systemic chronic inflammation with overexpression of human IL-6 (hIL-6) are in demand not only in the context of studying the molecula
Externí odkaz:
https://doaj.org/article/9a1753e943994903bedb8c05bd51a21e
Publikováno v:
Медицинская иммунология, Vol 25, Iss 3, Pp 617-624 (2023)
To date, much remains unclear about the pathogenesis of asthma, one of the most common chronic and highly heterogenic diseases of the respiratory system. The lack of specific and highly effective therapy in case of certain asthma subtypes requires th
Externí odkaz:
https://doaj.org/article/14bb635e313e49ddb898c76322cd8d41
Publikováno v:
Медицинская иммунология, Vol 25, Iss 3, Pp 477-482 (2023)
Itaconate is an immunoregulatory metabolite produced by myeloid cells and plays a key role in the regulation of the immune response. Itaconate, on the one hand, is able to suppress the activity of succinate dehydrogenase (SDH), thereby making a signi
Externí odkaz:
https://doaj.org/article/adc5f25ed0094ba39a6ba91ccbd9dd9e
Publikováno v:
Медицинская иммунология, Vol 22, Iss 5, Pp 827-836 (2020)
The COVID-19 pandemic, caused by the SARS-CoV-2 coronavirus, is unprecedented for the 21st century and has already affected countries with a total population of billions of people. The number of infected has already surpassed 30 million people and th
Externí odkaz:
https://doaj.org/article/e646707954d54239b8ff0728efec324e
Autor:
M. S. Drutskaya, E. O. Gubernatorova, E. A. Gorshkova, K.-S. N. Athertkhany, M. A. Nosenko, V. S. Gogoleva, O. A. Namakanova, R. V. Zvartsev, A. A. Kruglov, S. A. Nedospasov
Publikováno v:
Бюллетень сибирской медицины, Vol 18, Iss 1, Pp 38-48 (2019)
Cytokines comprise the molecular language of communication between the cells, which is needed to maintain the homeostatic functions of the body (including the immune system) and mediate various diseases. Many aspects of inflammation, autoimmune disea
Externí odkaz:
https://doaj.org/article/6a858b6469604f029e02385363b70423
Autor:
M. S. Drutskaya, E. A. Gorshkova, A. S. Zhdanova, K.-S. Atretkhany, V. S. Gogoleva, R. V. Zvartsev, A. A. Kruglov, S. A. Nedospasov
Publikováno v:
Медицинская иммунология, Vol 18, Iss 6, Pp 569-574 (2016)
Interleukin-6 (IL-6) exerts important functions on immune regulation. In case of high expression, IL-6 may promote autoimmune disorders, e.g., arthritis. Systemic IL-6 blockers based on monoclonal antibodies against IL-6, or its specific receptor sub
Externí odkaz:
https://doaj.org/article/12943e1321844d0c821fce0d89537cbd
Autor:
V G, Krut, I V, Astrakhantseva, S A, Chuvpilo, G A, Efimov, S G, Ambaryan, M S, Drutskaya, S A, Nedospasov
Publikováno v:
Doklady. Biochemistry and Biophysics
SARS-CoV-2 is a new coronavirus that is the cause of COVID-19 pandemic. To enter the cell, the virus interacts via its surface S protein with angiotensin-converting enzyme 2 (ACE2), the main entry receptor on the cell membrane. Most of protective ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa536ca6eb676a6ec20fed01315e64ce
http://europepmc.org/articles/PMC8649309
http://europepmc.org/articles/PMC8649309
Publikováno v:
Медицинская иммунология, Vol 17, Iss 5, Pp 395-406 (2015)
Immune checkpoints represent the system of inhibitory mechanisms regulating the activation of the immune response, preventing the autoimmune processes and modulating the immune response by decreasing the immune cell-mediated damage of tissues and org
Externí odkaz:
https://doaj.org/article/803b5b124b054e0eb125b23209da5286
Publikováno v:
Journal of Leukocyte Biology. 107:893-905
TNF is a key proinflammatory and immunoregulatory cytokine whose deregulation is associated with the development of autoimmune diseases and other pathologies. Recent studies suggest that distinct functions of TNF may be associated with differential e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fed047a6299fae1373da121ce1370c92
https://doi.org/10.1002/jlb.2mr0120-510r
https://doi.org/10.1002/jlb.2mr0120-510r
Publikováno v:
Molecular Biology. 53:665-680
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8902d6b6977f295c95ca91441881094e
https://doi.org/10.1134/s0026893319050078
https://doi.org/10.1134/s0026893319050078