Zobrazeno 1 - 5
of 5
pro vyhledávání: '"M S, Conners"'
Publikováno v:
Investigative ophthalmologyvisual science. 38(10)
Alkali burning of the rabbit cornea is a well-established model for the study of anterior surface inflammation, neovascularization, and wound-healing processes. 12-hydroxyeicosanoids have been implicated as mediators of such responses. 12(S)-hydroxye
Autor:
M S, Conners, R A, Stoltz, S C, Webb, J, Rosenberg, M W, Dunn, N G, Abraham, M, Laniado-Schwartzman
Publikováno v:
Investigative ophthalmologyvisual science. 36(5)
To characterize a model of contact lens-induced corneal inflammation in the closed eye, with respect to inflammatory parameters and the metabolism of arachidonic acid by homogenates of the corneal epithelium.Rabbit eyes were fitted with extended wear
Autor:
M S, Conners, R A, Stoltz, K L, Davis, M W, Dunn, N G, Abraham, R D, Levere, M, Laniado-Schwartzman
Publikováno v:
Investigative ophthalmologyvisual science. 36(5)
The authors have previously shown a marked increase in corneal epithelial arachidonic acid metabolism to 12-hydroxyeicosatetraenoic acid (12-HETE) and 12-hydroxyeicosatrienoic acid (12-HETrE) in a model of closed eye-contact lens wear. Their formatio
Autor:
M, Laniado-Schwartzman, Y, Lavrovsky, R A, Stoltz, M S, Conners, J R, Falck, K, Chauhan, N G, Abraham
Publikováno v:
The Journal of biological chemistry. 269(39)
12(R)-Hydroxy-5,8,14(Z,Z,Z)-eicosatrienoic acid (12(R)-HETrE) is an arachidonic acid metabolite formed by the corneal epithelium of several species, porcine leukocytes, and human and rat epidermal cells. It is a potent, stereospecific proinflammatory
Publikováno v:
Investigative ophthalmologyvisual science. 33(2)
Two biologically active cytochrome P-450 arachidonate metabolites previously were characterized: 12(R)-hydroxy-5,8,10,14-eicosatetraenoic acid (12(R)-HETE) and 12(R)-hydroxy-5,8,14-eicosatrienoic acid (12(R)-DH-HETE), which are endogenously formed in