Zobrazeno 1 - 10
of 127
pro vyhledávání: '"M Roselle Abraham"'
Autor:
Ryan P O'Hara, Edem Binka, Adityo Prakosa, Stefan L Zimmerman, Mark J Cartoski, M Roselle Abraham, Dai-Yin Lu, Patrick M Boyle, Natalia A Trayanova
Publikováno v:
eLife, Vol 11 (2022)
Hypertrophic cardiomyopathy (HCM) is associated with risk of sudden cardiac death (SCD) due to ventricular arrhythmias (VAs) arising from the proliferation of fibrosis in the heart. Current clinical risk stratification criteria inadequately identify
Externí odkaz:
https://doaj.org/article/41a1869802864523a63dd249be178dd7
Autor:
Xiaoping Lin, Steven Steinberg, Suresh K Kandasamy, Junaid Afzal, Blaid Mbiyangandu, Susan E Liao, Yufan Guan, Celia P Corona-Villalobos, Scot J Matkovich, Neal Epstein, Dotti Tripodi, Zhaoxia Huo, Garry Cutting, Theodore P Abraham, Ryuya Fukunaga, M Roselle Abraham
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0156065 (2016)
MicroRNAs (miRNAs) are recognized as important regulators of cardiac development, hypertrophy and fibrosis. Recent studies have demonstrated that genetic variations which cause alterations in miRNA:target interactions can lead to disease. We hypothes
Externí odkaz:
https://doaj.org/article/3083cf18fae34166813dbd5d0f4f83d3
Autor:
Arpana Vaniya, Anja Karlstaedt, Damla Gulkok, Tilo Thottakara, Yamin Liu, Sili Fan, Hannah Eades, Styliani Vakrou, Ryuya Fukunaga, Hilary J. Vernon, Oliver Fiehn, M. Roselle Abraham
Publikováno v:
Journal of Molecular and Cellular Cardiology Plus, Vol 8, Iss , Pp 100073- (2024)
Introduction: Hypertrophic cardiomyopathy (HCM) results from pathogenic variants in sarcomeric protein genes that increase myocyte energy demand and lead to cardiac hypertrophy. However, it is unknown whether a common metabolic trait underlies cardia
Externí odkaz:
https://doaj.org/article/d8cb9d6dcd734514bb112086143d8f7d
Autor:
Yiqiang Zhang, Tao-Sheng Li, Shuo-Tsan Lee, Kolja A Wawrowsky, Ke Cheng, Giselle Galang, Konstantinos Malliaras, M Roselle Abraham, Charles Wang, Eduardo Marbán
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e12559 (2010)
BackgroundIt has long been thought that mammalian cardiomyocytes are terminally-differentiated and unable to proliferate. However, myocytes in more primitive animals such as zebrafish are able to dedifferentiate and proliferate to regenerate amputate
Externí odkaz:
https://doaj.org/article/3ce886306d9044c3900d9ece50b203ee
Autor:
Dai-Yin Lu, Ioannis Ventoulis, Hongyun Liu, Bereketeab Haileselassie, Iraklis Pozios, Hsin-Yueh Liang, Lars L. Sorensen, Marco Canepa, Nicole Bavaro, Susan Phillip, M. Roselle Abraham, Theodore P. Abraham
Publikováno v:
International Journal of Cardiology. Cardiovascular Risk and Prevention, Vol 16, Iss , Pp 200166- (2023)
Objective: Hypertensive response to exercise (HRE) is observed in patients with hypertrophic cardiomyopathy (HCM) with normal resting blood pressure (BP). However, the prevalence or prognostic implications of HRE in HCM remain unclear. Methods: In th
Externí odkaz:
https://doaj.org/article/e9788cc7303a4d8f9ba9070b9b192ee2
Autor:
Jacob J. Mayfield, Andrew D. Leavitt, Talha Tanriverdi, Krishan Soni, Thomas A. Ports, M. Roselle Abraham
Publikováno v:
Journal of Thrombosis and Thrombolysis. 54:323-329
Autor:
Changxin Lai, Dan M. Popescu, Minglang Yin, Daiyin Lu, Julie K. Shade, Marc Engels, Edem Binka, stefan zimmerman, Jonathan Chrispin, M. Roselle Abraham, Natalia A. Trayanova
Publikováno v:
Heart Rhythm. 20:S46-S47
Autor:
Marc Engels, Konstantinos N. Aronis, Andreas S. Barth, M. Roselle Abraham, Natalia A. Trayanova, Jonathan Chrispin
Publikováno v:
Heart Rhythm. 20:S669
Autor:
Kasra Nezamabadi, Jacob Mayfield, Pengyuan Li, Gabriela V Greenland, Sebastian Rodriguez, Bahadir Simsek, Parvin Mousavi, Hagit Shatkay, M Roselle Abraham
Publikováno v:
Journal of the American Medical Informatics Association : JAMIA. 29(11)
Objective Abnormalities in impulse propagation and cardiac repolarization are frequent in hypertrophic cardiomyopathy (HCM), leading to abnormalities in 12-lead electrocardiograms (ECGs). Computational ECG analysis can identify electrophysiological a
Autor:
Stefan L. Zimmerman, Sagar Goyal, Hulya Yalcin, M. Roselle Abraham, Effrosyni Kontari, Shibani M. Kudchadkar, Celia P. Corona-Villalobos, Dai Yin Lu, Gabriela V. Greenland, Ioannis Ventoulis, Styliani Vakrou, Hongyun Liu, Theodore P. Abraham
Publikováno v:
American Heart Journal. 219:58-69
Background It is unknown whether sex-specific differences in mortality observed in HCM are due to older age of women at presentation, or whether women have greater degree of LV myopathy than men. Methods We retrospectively compared clinical/imaging c