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Do Observer Effects Matter? A Comment on Langenburg, Bochet, and Ford

Autor: R. Koppl, D. Charlton, I. Kornfield, D. Krane, M. Risinger, C. Robertson, M. Saks, W. Thompson

Publikováno v: Forensic Science Policy & Management: An International Journal. 6:1-6

We identify methodological problems in Langenburg et al. (2014), which undermine its conclusions about the size of the observer effect problem and the importance of sequential unmasking as a solution. The scoring method of Langenburg et al. (2014) ap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::51ffbda59a06e88d87834a41d8d9a2c8
https://doi.org/10.1080/19409044.2014.995385

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Akademický článek

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Autor: George M. Risinger, Carol J. Haaksma, Beverly J. Crider, Eric W. Howard, James J. Tomasek

Publikováno v: The Journal of investigative dermatology

Myofibroblasts are contractile, smooth muscle-like cells that are characterized by the de novo expression of smooth muscle α-actin (SMαA) and normally function to assist in wound closure, but have been implicated in pathological contractures. Trans

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69b4aa0ae68293544ea949412a398d9e
http://europepmc.org/articles/PMC3199034

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TGF-β suppresses the upregulation of MMP-2 by vascular smooth muscle cells in response to PDGF-BB

Autor: Dawn L. Updike, George M. Risinger, James J. Tomasek, Elizabeth C. Bullen, Eric W. Howard

Publikováno v: American Journal of Physiology-Cell Physiology. 298:C191-C201

During platelet-derived growth factor (PDGF)-BB-mediated recruitment to neovascular sprouts, vascular smooth muscle cells (VSMCs) dedifferentiate from a contractile to a migratory phenotype. This involves the downregulation of contractile markers suc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5583ba16f6e3ee06ffcf501d468ba87
https://doi.org/10.1152/ajpcell.00417.2008

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Matrix Metalloproteinase-2 Expression by Vascular Smooth Muscle Cells Is Mediated by Both Stimulatory and Inhibitory Signals in Response to Growth Factors

Autor: George M. Risinger, Tamara S. Hunt, Elizabeth C. Bullen, Dawn L. Updike, Eric W. Howard

Publikováno v: Journal of Biological Chemistry. 281:25915-25925

In response to growth factors, vascular smooth muscle cells (VSMCs) undergo a phenotypic modulation from a contractile, non-proliferative state to an activated, migratory state. This transition is characterized by changes in their gene expression pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b47cf399ffb0d4da2e1fb0afe1ee74e7
https://doi.org/10.1074/jbc.m513513200

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Crosslinks and crosstalkHuman cancer syndromes and DNA repair defects

Autor: M RISINGER, J GRODEN

Publikováno v: Cancer Cell. 6:539-545

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::71045abcdf2e34cf184dc0ebb7ccd788
https://doi.org/10.1016/s1535-6108(04)00338-1

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Self-association and conformational properties of RAG1: implications for formation of the V(D)J recombinase

Autor: Negar S. Rahman, LeAnn J. Godderz, Karla K. Rodgers, Janeen L. Arbuckle, George M. Risinger

Publikováno v: Nucleic Acids Research. 31:2014-2023

RAG1 and RAG2 catalyze the initial DNA cleavage steps in V(D)J recombination. Fundamental properties of these proteins remain largely unknown. Here, self-association and conformational properties of murine core RAG1 (residues 384-1008) were examined.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd1eb707f811bb32a30099c4ce8d6d7a
https://doi.org/10.1093/nar/gkg281

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